DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpc2 and AT5G48970

DIOPT Version :9

Sequence 1:	NP_001246511.1	Gene:	Tpc2 / 37983	FlyBaseID:	FBgn0035078	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	NP_199708.1	Gene:	AT5G48970 / 834956	AraportID:	AT5G48970	Length:	339	Species:	Arabidopsis thaliana

Alignment Length:	320	Identity:	103/320 - (32%)
Similarity:	165/320 - (51%)	Gaps:	39/320 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVT-------NHKG-SKYRGVIHAFKSVYAEE 66
            |:.|..|.|:|..:|::|.||||:|||||:|:||.|       |..| |||.|::.|.|.::.||
plant    19 LIDASAGAISGGVSRSVTSPLDVIKIRFQVQLEPTTSWGLVRGNLSGASKYTGMVQATKDIFREE 83

  Fly    67 GMRGMFRGHNSGQVLSISYALVQFWSYEQLRSMA----HQFDYWRERPFLMFFICGGIAGCLGAV 127
            |.||.:||:....::.:.|..:||....:|:|.|    ...|:....|:|. |:.|.:|||...:
plant    84 GFRGFWRGNVPALLMVMPYTSIQFTVLHKLKSFASGSTKTEDHIHLSPYLS-FVSGALAGCAATL 147

  Fly   128 AAQPFDVVRTQMVA-ADPSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANF--- 188
            .:.|||::||.:.: .:|....:..:.|.   .:.:..|..||..||..|||::.|..|..|
plant   148 GSYPFDLLRTILASQGEPKVYPTMRSAFV---DIIQSRGIRGLYNGLTPTLVEIVPYAGLQFGTY 209

  Fly   189 -LFYKYL---NAAVLMAKPPDQRQEIHGAF-LFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQ- 247
             :|.:::   |...|.:|.|........:| ||:.|..:|..||::.:|.|::|||.|:...::
plant   210 DMFKRWMMDWNRYKLSSKIPINVDTNLSSFQLFICGLGAGTSAKLVCHPLDVVKKRFQIEGLQRH 274

  Fly   248 -------ERKTFGRNPECPTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYD 300
                   ||:.: ||     :|..:......||..|.|||::|:.:||....||.|..|:
plant   275 PRYGARVERRAY-RN-----MLDGLRQIMISEGWHGLYKGIVPSTVKAAPAGAVTFVAYE 328

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	PTZ00169	23..304	CDD:240302	98/307 (32%)
		Mito_carr	23..99	CDD:278578	34/83 (41%)
		Mito_carr	108..194	CDD:278578	26/90 (29%)
		Mito_carr	216..307	CDD:278578	29/93 (31%)
AT5G48970	NP_199708.1	Mito_carr	18..116	CDD:395101	39/96 (41%)
		Mito_carr	128..218	CDD:395101	26/93 (28%)
		Mito_carr	236..334	CDD:395101	31/99 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	77	1.000	Domainoid score	I3085
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	181	1.000	Inparanoid score	I1450
OMA	1	1.010	-	-		QHG55227
OrthoDB	1	1.010	-	-		D1454699at2759
OrthoFinder	1	1.000	-	-		FOG0001923
OrthoInspector	1	1.000	-	-		mtm1203
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24089
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2188
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.940