Protein Alignment Tpc2 and SLC25A16

DIOPT Version :9

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_689920.1
• Gene: SLC25A16 / 8034
• HGNCID: 10986
• Length: 332
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 76/318 - (23%)
• Similarity: 138/318 - (43%)
• Gaps: 46/318 - (14%)

  Fly    10 LMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYAEEGMRGMFRG 74
            |...:.|||||...:|...|||.:|:..|..     ||. .|:.||..|.::|..:||..|:::|
Human    37 LRSFLAGGIAGCCAKTTVAPLDRVKVLLQAH-----NHH-YKHLGVFSALRAVPQKEGFLGLYKG 95

  Fly    75 HNSGQVLSISYALVQFWSYEQLRSM----------AHQFDYWRERPFLMFFICGGIAGCLGAVAA 129
            :.:..:....|..:||.::|..:::          .|:            .:.|.:||....:..
Human    96 NGAMMIRIFPYGAIQFMAFEHYKTLITTKLGISGHVHR------------LMAGSMAGMTAVICT 148

  Fly   130 QPFDVVRTQMVAADPSSRRSQMNTFTGLRKVYKME-GWMGLSRGLPFTLVQVFPLVGANFLFYKY 193
            .|.|:||.:: |.......|........:.:|..| |:.|..|||..|::.:.|..|.:|..:..
Human   149 YPLDMVRVRL-AFQVKGEHSYTGIIHAFKTIYAKEGGFFGFYRGLMPTILGMAPYAGVSFFTFGT 212

  Fly   194 L------NAAVLMAKPPDQRQEIHGAFLFLN---GALSGVLAKMIVYPADLLKKRIQLMAFKQER 249
            |      :|..|:.:|......:......:|   |.::|.:|:.|.||.|:.::|:||.....|.
Human   213 LKSVGLSHAPTLLGRPSSDNPNVLVLKTHVNLLCGGVAGAIAQTISYPFDVTRRRMQLGTVLPEF 277

  Fly   250 KTFGRNPECPTILGCITTTFREEGI-GGFYKGMLPTLLKAGLMSAVYFSIYDMFKRHY 306
            :      :|.|:...:...:...|| .|.|:|:....::.....||.|:.|::.|:.:
Human   278 E------KCLTMRDTMKYVYGHHGIRKGLYRGLSLNYIRCIPSQAVAFTTYELMKQFF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	PTZ00169	23..304	CDD:240302	69/301 (23%)
		Mito_carr	23..99	CDD:278578	21/75 (28%)
		Mito_carr	108..194	CDD:278578	20/86 (23%)
		Mito_carr	216..307	CDD:278578	24/95 (25%)
SLC25A16	NP_689920.1	Mito_carr	33..125	CDD:278578	27/93 (29%)
		Solcar 1	34..120		27/88 (31%)
		PTZ00169	36..330	CDD:240302	76/318 (24%)
		Solcar 2	128..216		22/100 (22%)
		Mito_carr	131..214	CDD:278578	21/95 (22%)
		Mito_carr	238..330	CDD:278578	24/98 (24%)
		Solcar 3	238..328		24/95 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810