DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tpc2 and Slc25a42

DIOPT Version :9

Sequence 1:	NP_001246511.1	Gene:	Tpc2 / 37983	FlyBaseID:	FBgn0035078	Length:	323	Species:	Drosophila melanogaster
Sequence 2:	XP_006253013.1	Gene:	Slc25a42 / 689414	RGDID:	1592346	Length:	329	Species:	Rattus norvegicus

Alignment Length:	192	Identity:	58/192 - (30%)
Similarity:	88/192 - (45%)	Gaps:	17/192 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSV---YAEEGMRGM 71
            |...:.|.:|||..:|...|||..||.||:         .||......||:.:   |..||...:
  Rat    79 LSSLLSGALAGALAKTAVAPLDRTKIIFQV---------SSKRFSAKEAFRLLYFTYLNEGFLSL 134

  Fly    72 FRGHNSGQVLSISYALVQFWSYEQL-RSMAHQFDYWRER-PFLMFFICGGIAGCLGAVAAQPFDV 134
            :||:::..|..|.||.:||.::|:. |.:.|.:.:..|. |.....:.|.:||...|....|.|:
  Rat   135 WRGNSATMVRVIPYAAIQFSAHEEYKRILGHYYGFRGEALPPWPRLLAGALAGTTAASLTYPLDL 199

  Fly   135 VRTQMVAADPSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFLFYKYLNA 196
            ||.:| |..|....|  |.|....::.:.||...|..|...|::.|.|..|.:|..|:.|.:
  Rat   200 VRARM-AVTPKEMYS--NIFHVFIRISREEGLKTLYFGFTPTVLGVIPYAGLSFFTYESLKS 258

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	PTZ00169	23..304	CDD:240302	53/179 (30%)
		Mito_carr	23..99	CDD:278578	25/79 (32%)
		Mito_carr	108..194	CDD:278578	26/86 (30%)
		Mito_carr	216..307	CDD:278578
Slc25a42	XP_006253013.1	Mito_carr	74..167	CDD:278578	31/96 (32%)
Slc25a42	XP_006253013.1	Mito_carr	<192..259	CDD:278578	21/70 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0752
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900