DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tpc2 and Slc25a19

DIOPT Version :9

Sequence 1:NP_001246511.1 Gene:Tpc2 / 37983 FlyBaseID:FBgn0035078 Length:323 Species:Drosophila melanogaster
Sequence 2:NP_001239313.1 Gene:Slc25a19 / 67283 MGIID:1914533 Length:318 Species:Mus musculus


Alignment Length:296 Identity:107/296 - (36%)
Similarity:164/296 - (55%) Gaps:6/296 - (2%)


- Green bases have known domain annotations that are detailed below.


  Fly     9 QLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPV-TNHKGSKYRGVIHAFKSVYAEEGMRGMF 72
            :|..||.|.::|..||.:..||||:|||||:|:|.: .:...:||.|:..|.|.:..|||.|..:
Mouse    15 KLEVAVAGSVSGFVTRALISPLDVIKIRFQLQIERLCPSDPNAKYHGIFQAAKQILQEEGPRAFW 79

  Fly    73 RGHNSGQVLSISYALVQFWSYEQLRSMAHQFDYWRERPFLMFFICGGIAGCLGAVAAQPFDVVRT 137
            :||...|:|||.|..|||.::|:|..:.:|.:.::...|...|:|||::.....:...|.||:||
Mouse    80 KGHVPAQILSIGYGAVQFLAFEELTELLYQANLYQTHQFSAHFVCGGLSAGTATLTVHPVDVLRT 144

  Fly   138 QMVA-ADPSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFLFYKYLNAAVLMA 201
            ::.| .:|   :...|....:|.:||.||.....:||..|::.:||..|..|..|:.|..|....
Mouse   145 RLAAQGEP---KIYNNLREAIRTMYKTEGPFVFYKGLTPTVIAIFPYAGLQFSCYRSLKRAYDWL 206

  Fly   202 KPPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQERKTFGRNPECPTILGCIT 266
            .|||.:|..:...| |.|..|||::|...||.||:|||:|:..|:..|..||:......:|....
Mouse   207 IPPDGKQTGNLKNL-LCGCGSGVISKTFTYPLDLIKKRLQVGGFEHARSAFGQVRSYRGLLDLTQ 270

  Fly   267 TTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMF 302
            ...:|||..||:||:.|:|:||.|.:...|..|::|
Mouse   271 QVLQEEGTRGFFKGLSPSLMKAALSTGFMFFWYELF 306

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tpc2NP_001246511.1 PTZ00169 23..304 CDD:240302 102/282 (36%)
Mito_carr 23..99 CDD:278578 34/76 (45%)
Mito_carr 108..194 CDD:278578 26/86 (30%)
Mito_carr 216..307 CDD:278578 34/87 (39%)
Slc25a19NP_001239313.1 Solcar 1 13..106 39/90 (43%)
Mito_carr 16..108 CDD:395101 39/91 (43%)
Solcar 2 116..202 27/88 (31%)
Mito_carr 118..203 CDD:395101 27/87 (31%)
Mito_carr 212..311 CDD:395101 36/96 (38%)
Solcar 3 214..309 35/94 (37%)
Substrate recognition. /evidence=ECO:0000250 241..246 3/4 (75%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167833008
Domainoid 1 1.000 87 1.000 Domainoid score I7997
eggNOG 1 0.900 - - E1_KOG0752
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 225 1.000 Inparanoid score I3489
Isobase 1 0.950 - 0 Normalized mean entropy S1857
OMA 1 1.010 - - QHG55227
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0001923
OrthoInspector 1 1.000 - - otm43753
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24089
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X2188
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1312.810

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