Protein Alignment Tpc2 and mfrn

DIOPT Version :10

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_651600.1
• Gene: mfrn / 43353
• FlyBaseID: FBgn0039561
• Length: 379
• Species: Drosophila melanogaster
• Alignment Length: 316
• Identity: 76/316 - (24%)
• Similarity: 124/316 - (39%)
• Gaps: 58/316 - (18%)

  Fly     1 MPENSVVVQLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYAE 65
            :|..||.|.:   ..|.|||.....:..|||.:|.|.|....|..|      ..::...:::...
  Fly     9 LPTTSVGVNM---TAGAIAGVLEHVVMYPLDSVKTRMQSLSPPTKN------MNIVSTLRTMITR 64

  Fly    66 EGMRGMFRGHNSGQVLSISYA-LVQFWSYEQLRSMAHQFDYWRERPFLMFFICGGIAGCLGAVAA 129
            ||:....|| .|..||....| .:.|.:||..:.:..:|...|.   |.:.|.|.:|..:....:
  Fly    65 EGLLRPIRG-ASAVVLGAGPAHSLYFAAYEMTKELTAKFTSVRN---LNYVISGAVATLIHDAIS 125

  Fly   130 QPFDVVRTQMVAADPSSRRSQM--NTFTG----LRKVYKMEGWMGLSRGLPFTLVQVFPLVGANF 188
            .|.||::          :|.||  :.:|.    :|.:||.||:....|.....||...|....:|
  Fly   126 SPTDVIK----------QRMQMYNSPYTSVVSCVRDIYKREGFKAFYRAYGTQLVMNLPYQTIHF 180

  Fly   189 LFYKYLNAAVLMAK---PPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQERK 250
            ..|::....:.:.:   ||     :|.|    .||.:|..|..:..|.|::             |
  Fly   181 TTYEFFQNKMNLERKYNPP-----VHMA----AGAAAGACAAAVTTPLDVI-------------K 223

  Fly   251 TFGRNPECPTILGCITTT---FREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMFK 303
            |.....|.....|.|..:   :...|..||::|....:|.:...:|:.:|.|:.||
  Fly   224 TLLNTQETGLTRGMIEASRKIYHMAGPLGFFRGTTARVLYSMPATAICWSTYEFFK 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	19/76 (25%)
		Mito_carr	108..194	CDD:395101	22/91 (24%)
		Mito_carr	216..307	CDD:395101	21/91 (23%)
mfrn	NP_651600.1	PTZ00168	17..280	CDD:185494	72/308 (23%)