Protein Alignment Tpc2 and Tyler

DIOPT Version :9

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_608327.2
• Gene: Tyler / 3772349
• FlyBaseID: FBgn0031038
• Length: 441
• Species: Drosophila melanogaster
• Alignment Length: 411
• Identity: 82/411 - (19%)
• Similarity: 152/411 - (36%)
• Gaps: 116/411 - (28%)

  Fly    10 LMQAVGGGIAGAATRTITQPLDVLKIRFQMQ----VEPVTN------HKG--------------- 49
            :.|.|...:.|..|..:..||:|:|.|.|.|    ..|..:      |.|
  Fly    46 MQQVVSALVGGLITTFVVTPLEVVKTRVQTQHAIRQRPTVSKLCYVYHNGLMTHVCRSSDICVPK 110

  Fly    50 --------SKYRGVIHAFKSVYAEEGMRGMFRGHNSGQVLSISYALVQFWSYEQLR-SMAHQF-- 103
                    ...||.:.||..:....|..|::.|.:...|.::...::.|.:||.:: |::|.:
  Fly   111 PGRDPQNLRPLRGAMDAFVKIVCTSGFSGLWAGLSPTLVSALPSTIIYFLTYEYIKNSLSHIYLV 175

  Fly   104 -DYWRER-----------------------------------PFLMFFICGGIAGCLGAVAAQPF 132
             ..:.|.                                   |:.:....|..:..:...|..|.
  Fly   176 SQKFEESGMKDQVPGADGGDPLDQATRGINVSATAPVSTASLPYYVPMASGICSRTIVVTAITPI 240

  Fly   133 DVVRTQMVAADPSSRRSQMNTFTG----LRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFLFYKY 193
            ::||.:|        :|:..|:..    ||.:.:..|.:||.||.|.|:::..|..|..:..|:.
  Fly   241 EMVRIKM--------QSEYMTYAELWRVLRSLIRQHGILGLWRGWPPTVMRDAPFSGTYWAVYEA 297

  Fly   194 LNAAVLMAKPPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQL-----MAFKQERKTFG 253
            :..|..:.:|.       ..|.||.||:||.:|..:..|.||:....|:     :.:::.....|
  Fly   298 IKRAFSVTEPT-------FLFSFLTGAISGAVATFVTMPFDLITTHTQIELGQDVLYEEIGAGTG 355

  Fly   254 -----------RNPEC------PTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDM 301
                       :.|:.      |::|..:...:|.:|:.|.|.|::|.:|:.....|:..|.::.
  Fly   356 AGTGTGAGARPKTPQSAVANSRPSVLSRMRQIYRLQGVRGLYVGVMPRMLRVVPACAIMISTFEY 420

  Fly   302 FKR---HYIAPMKEAEKNRQK 319
            .|.   ||...::||...|.:
  Fly   421 SKSFFFHYNLDLQEAAYRRSQ 441

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	PTZ00169	23..304	CDD:240302	73/378 (19%)
		Mito_carr	23..99	CDD:278578	22/109 (20%)
		Mito_carr	108..194	CDD:278578	22/124 (18%)
		Mito_carr	216..307	CDD:278578	26/115 (23%)
Tyler	NP_608327.2	Mito_carr	41..171	CDD:278578	26/124 (21%)
		Mito_carr	216..302	CDD:278578	21/93 (23%)
		Mito_carr	306..429	CDD:278578	28/129 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45441421
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840