Protein Alignment Tpc2 and hpo-12

DIOPT Version :9

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001379467.1
• Gene: hpo-12 / 36804989
• WormBaseID: WBGene00016588
• Length: 313
• Species: Caenorhabditis elegans
• Alignment Length: 311
• Identity: 108/311 - (34%)
• Similarity: 159/311 - (51%)
• Gaps: 25/311 - (8%)

  Fly     2 PE--NSVVVQLMQAVGGGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYA 64
            ||  |..:.....:..|..:|..||.|.|||||||||||:|.||:...|..||:||:.:...:..
 Worm     6 PEAINEPLTSAEYSEAGLASGIVTRMIIQPLDVLKIRFQLQEEPIRGKKSGKYKGVMQSIFLITR 70

  Fly    65 EEGMRGMFRGHNSGQVLSISYALVQFWSYEQLRSMAHQF---DYWRERPFLMFFICGGIAGCLGA 126
            |||....::||...|.||.:|.||||.|:|.|...|.:.   |....|. ...|.||.::|||..
 Worm    71 EEGAHAFWKGHIPAQGLSATYGLVQFSSFEWLSQQAAKVIPADNQSVRS-TSDFACGALSGCLAM 134

  Fly   127 VAAQPFDVVRTQMVAADPSSRRSQMNTFTG----LRKVYKMEGWMGLSRGLPFTLVQVFPLVGAN 187
            .||.|.||:||::||     :::....:||    ::.:::.||..|..||...::||:.|..|..
 Worm   135 TAAMPLDVIRTRLVA-----QKAGHAVYTGTMHAVKHIWEKEGIAGYFRGWVPSVVQIAPFTGMQ 194

  Fly   188 FLFYKYLNAAVLMAKPPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQERKTF 252
            |..|.     ..|...|....|..|| || :||::|.:||.::||.|:::.|:|:..|  ||..|
 Worm   195 FALYN-----CFMDLWPFNGYESAGA-LF-SGAMAGTVAKTVLYPLDMVRHRLQMNGF--ERAGF 250

  Fly   253 GRNPE-CPTILGCITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMF 302
            |:... ...:...|....:.|...|.:||:.|:.:||...|...|..|::|
 Worm   251 GKTSNYSQGLFKTIGMVVKNESWYGLFKGLWPSQIKAAANSGCAFLFYEIF 301

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	PTZ00169	23..304	CDD:240302	103/288 (36%)
		Mito_carr	23..99	CDD:278578	38/75 (51%)
		Mito_carr	108..194	CDD:278578	29/89 (33%)
		Mito_carr	216..307	CDD:278578	28/88 (32%)
hpo-12	NP_001379467.1	Mito_carr	11..102	CDD:395101	39/90 (43%)
		Mito_carr	115..209	CDD:395101	31/104 (30%)
		Mito_carr	216..309	CDD:395101	29/89 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157400
Domainoid	1	1.000	84	1.000	Domainoid score	I5266
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	182	1.000	Inparanoid score	I2639
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55227
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001923
OrthoInspector	1	1.000	-	-		otm14068
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24089
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2188
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	10.000