Protein Alignment Tpc2 and Slc25a43

DIOPT Version :10

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: NP_001078966.1
• Gene: Slc25a43 / 194744
• MGIID: 2684854
• Length: 341
• Species: Mus musculus
• Alignment Length: 316
• Identity: 66/316 - (20%)
• Similarity: 136/316 - (43%)
• Gaps: 65/316 - (20%)

  Fly    17 GIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYAEEGMRGMFRGHNSGQVL 81
            |:|||.:.::|.||::..:  ..||..|.:|.    .|:....:.|:..||.|.:::|:....:.
Mouse    20 GLAGAFSLSLTAPLELATV--LAQVGKVQSHS----LGLWATGRRVWLSEGPRALWKGNGVACLR 78

  Fly    82 SISYALVQFWSYEQLRSMAHQFDYWRERPFLMFF-------------ICGGIAGCLGAVAAQPFD 133
            ....::||..:|               |.|::.|             :.|.:||.:..:...|.|
Mouse    79 LFPCSMVQLAAY---------------RKFVVLFMDDLGRISQWSSIVTGSLAGMVSTIVTYPTD 128

  Fly   134 VVRTQMVAAD--PSSRRSQMNTFTGLRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFLFYKYLNA 196
            :::|:::..:  ..|.|..::.|:   .:|:.||::.|.||:..|::...|....:.|.  |:|.
Mouse   129 LIKTRLMVQNVLEPSYRGLIHAFS---TIYQQEGFLALYRGVSLTVLGAVPFSAGSLLV--YMNL 188

  Fly   197 AVLMAKPPDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMAFKQERKTFGRNPECPTI 261
            ..:...|.|:...:..   |.|..::..:::.:.:|.|.:|:::|           .::|..|..
Mouse   189 EKVWNGPRDRFSHLQN---FANVCVAAAVSQTLSFPFDTVKRKMQ-----------AQSPYLPHY 239

  Fly   262 LG----------CITTTFREEGIGGFYKGMLPTLLKAGLMSAVYFSIYDMFKRHYI 307
            .|          |.....:.:|:.|.:.|:...|||......|.||:::..||.::
Mouse   240 GGVDVHFSGAADCFRQIVKTQGVLGLWNGLTANLLKVVPYFGVMFSMFEFCKRIFL 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	16/75 (21%)
		Mito_carr	108..194	CDD:395101	21/100 (21%)
		Mito_carr	216..307	CDD:395101	21/100 (21%)
Slc25a43	NP_001078966.1	Solcar 1	11..101		23/101 (23%)
		PTZ00169	17..275	CDD:240302	59/294 (20%)
		Solcar 2	105..185		18/84 (21%)
		Solcar 3	200..298		21/110 (19%)