Protein Alignment Tpc2 and slc25a43

DIOPT Version :10

• Sequence 1: NP_001246511.1
• Gene: Tpc2 / 37983
• FlyBaseID: FBgn0035078
• Length: 323
• Species: Drosophila melanogaster
• Sequence 2: XP_002934585.2
• Gene: slc25a43 / 100485727
• XenbaseID: XB-GENE-6258507
• Length: 342
• Species: Xenopus tropicalis
• Alignment Length: 327
• Identity: 85/327 - (25%)
• Similarity: 146/327 - (44%)
• Gaps: 73/327 - (22%)

  Fly    16 GGIAGAATRTITQPLDVLKIRFQMQVEPVTNHKGSKYRGVIHAFKSVYAEEGMRGMFRGHNSGQV 80
            |||||.|:||:|.||||:||..|:.    |.|....:.|   .||.:...||:|.:::|:.:..|
 Frog    19 GGIAGVASRTLTAPLDVVKILSQVG----TFHTKQGFAG---TFKLLCKAEGVRALWKGNLTACV 76

  Fly    81 LSISYALVQFWSYEQLRSM----AHQFDYWRERPFLMFFICGGIAGCLGAVAAQPFDVVRTQMVA 141
            ....|:.||..:|.:...:    ..:...|:.      .:.||:||.:.||...|.|:|:|:::.
 Frog    77 RLFPYSAVQLAAYRRFTLLFMDDLGRISKWQA------IVSGGLAGVVAAVVIYPTDIVKTRLIV 135

  Fly   142 ADPSSRRSQMNTFTG----LRKVYKMEGWMGLSRGLPFTLVQVFPLVGANFLFYKYLNAAVLMAK 202
                 :.|...|:.|    |..:|..||:..|.||:..|::...|...:  ||:..::...:..:
 Frog   136 -----QNSLEPTYRGIIHALCSIYYQEGFRSLYRGISLTVLGAIPFSAS--LFFMNISLDRIWQE 193

  Fly   203 P-----PDQRQEIHGAFLFLNGALSGVLAKMIVYPADLLKKRIQLMA-FKQERKTFGRNPECPTI 261
            |     |.|.        |.||.|:..:|:.:.:|.:.:|:::|..: |.         |.|..:
 Frog   194 PGVCLSPLQH--------FANGCLAAAVAQTMSFPFETVKRKMQAQSQFL---------PHCGGV 241

  Fly   262 -------LGCITTTFREEGIGGFYKGMLPTLLKA----GLMSAVYFSIYDMFKR-------HYIA 308
                   |.|.....:.:|:...:.|:...:||.    |||    ||.|:..||       :.|:
 Frog   242 DVHFNGMLNCFRQIVKTKGVLSLWNGLTANILKVVPYFGLM----FSTYECCKRFCLYQNGYIIS 302

  Fly   309 PM 310
            |:
 Frog   303 PL 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tpc2	NP_001246511.1	Mito_carr	23..99	CDD:395101	24/75 (32%)
		Mito_carr	108..194	CDD:395101	24/89 (27%)
		Mito_carr	216..307	CDD:395101	25/109 (23%)
slc25a43	XP_002934585.2	PTZ00169	17..274	CDD:240302	73/291 (25%)