Protein Alignment NaCP60E and Catsper2

DIOPT Version :10

• Sequence 1: NP_001261172.1
• Gene: NaCP60E / 37981
• FlyBaseID: FBgn0085434
• Length: 2896
• Species: Drosophila melanogaster
• Sequence 2: NP_694715.2
• Gene: Catsper2 / 212670
• MGIID: 2387404
• Length: 588
• Species: Mus musculus
• Alignment Length: 323
• Identity: 80/323 - (24%)
• Similarity: 152/323 - (47%)
• Gaps: 69/323 - (21%)

  Fly  1747 VVDTPAFEWFVLVLIFASSITLCFEDINLDKNKT----LKRVLYWINFSFCLIFVVEMILKWLAL 1807
            |:|:..|..|::.|||.::..|..|...::...|    :|..|...::...|.|:||::|.|||
Mouse   102 VLDSSVFSKFIISLIFLNTFVLMVEIELMESTNTALWPVKLALEVADWFILLSFIVEILLMWLA- 165

  Fly  1808 GFSKYFTSFWTILDFIIVFVSVFSLLIEENENLKV------LRSLRTLRALRPLRAISRWQGMRI 1866
            .||.::...|.:.||   ||::.|||.|....|.|      |:.||..|.||.|:..:|::.:::
Mouse   166 SFSLFWKDAWNVFDF---FVTLLSLLPELVVLLGVPAHSVWLQLLRVCRVLRSLKLFARFRQIKV 227

  Fly  1867 VVNALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVNEMGELLPITEVNDKWDCIEQNY 1931
            ::.||:.|:.|:..:|::.|:|:.||::.||.|| .::.:...|               .:|.|.
Mouse   228 ILLALVRALKSMTFLLMLLLIFFYIFAVTGVYFF-REYSRSTIE---------------GLEYNM 276

  Fly  1932 TW---INSKITFDHVGMGYLALLQVATFEGWMEVMADAVDARGVDLQPQREANLYAYIYFVIFIV 1993
            .:   :||.:|          :..:.|.:.|..|:.|.       .:....:.:::.||.:::::
Mouse   277 FFSDLLNSLVT----------VFILFTLDHWYAVLQDI-------WKVPESSRVFSSIYVILWLL 324

  Fly  1994 CGSFFTLNLFIGVIIDNFNMLKKKYEGGVLEMFLTESQKH----YYTAMKKLGRKKPQKVIKR 2052
            .||....|:.:.:::.||..::.:         |:|...|    |...|.|      |::|:|
Mouse   325 LGSIIFRNIIVAMMVTNFQNIRSE---------LSEEMSHLEVQYKADMFK------QQIIQR 372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaCP60E	NP_001261172.1	Ion_trans	125..371	CDD:459842
		Ion_trans	687..902	CDD:459842
		Ion_trans	1751..2019	CDD:459842	69/280 (25%)
		Na_channel_gate	2009..2063	CDD:240441	11/48 (23%)
		Ion_trans	2067..2320	CDD:459842
		GPHH	2332..2378	CDD:465306
Catsper2	NP_694715.2	Ion_trans	105..350	CDD:459842	69/290 (24%)