Protein Alignment NaCP60E and CATSPER2

DIOPT Version :9

• Sequence 1: NP_001261172.1
• Gene: NaCP60E / 37981
• FlyBaseID: FBgn0085434
• Length: 2896
• Species: Drosophila melanogaster
• Sequence 2: NP_001269239.1
• Gene: CATSPER2 / 117155
• HGNCID: 18810
• Length: 534
• Species: Homo sapiens
• Alignment Length: 419
• Identity: 84/419 - (20%)
• Similarity: 172/419 - (41%)
• Gaps: 105/419 - (25%)

  Fly  1635 LAMAQKTEQSQSTAPDATQKPSAFTRLTEKPWHCLVSYVDDLTVGGRRNSQGAYNDP-------- 1691
            :|..|:.||.|....||.:     :||.:.  ..|:.::..|:....|::.....||
Human     7 MAAYQQEEQMQLPRADAIR-----SRLIDT--FSLIEHLQGLSQAVPRHTIRELLDPSRQKKLVL 64

  Fly  1692 ------MTFPSYGATKAAKVPDDCFPQKCYDHFYFRCP----------WFMSCMDTQSAKHWTRV 1740
                  :.|    :.|..::......|:.....:.||.          |.:.|
Human    65 GDQHQLVRF----SIKPQRIEQISHAQRLLSRLHVRCSQRPPLSLWAGWVLEC------------ 113

  Fly  1741 RTAVLTVVDTPAFEWFVLVLIFASSITLCFEDINLDKNKT----LKRVLYWINFSFCLIFVVEMI 1801
                      |.|:.|::.|:|.::|.|..|...|:...|    ||..|....:...|||::|::
Human   114 ----------PLFKNFIIFLVFLNTIILMVEIELLESTNTKLWPLKLTLEVAAWFILLIFILEIL 168

  Fly  1802 LKWLALGFSKYFTSFWTILDFIIVFVSVFS---LLIEENENLKVLRSLRTLRALRPLRAISRWQG 1863
            ||||: .||.::.|.|.:.||::..:|:..   :|:........|:.||..|.||.|:.:::::.
Human   169 LKWLS-NFSVFWKSAWNVFDFVVTMLSLLPEVVVLVGVTGQSVWLQLLRICRVLRSLKLLAQFRQ 232

  Fly  1864 MRIVVNALMYAIPSIFNVLLVCLVFWLIFSIMGVQFFGGKFFKCVNEMGELLPITEVNDKWDCIE 1928
            ::|::..|:.|:.|:..:|::.|:|:.||::.||..|
Human   233 IQIIILVLVRALKSMTFLLMLLLIFFYIFAVTGVYVF---------------------------- 269

  Fly  1929 QNYTW-----INSKITFDHVGMGYLALLQVATFEGWMEVMADAVDARGVDLQPQREANLYAYIYF 1988
            ..||.     :...:.|..:....:.:..:.|.:.|..::.|......|       :.:::.|||
Human   270 SEYTRSPRQDLEYHVFFSDLPNSLVTVFILFTLDHWYALLQDVWKVPEV-------SRIFSSIYF 327

  Fly  1989 VIFIVCGSFFTLNLFIGVIIDNFNMLKKK 2017
            :::::.||....::.:.:::.||..::|:
Human   328 ILWLLLGSIIFRSIIVAMMVTNFQNIRKE 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NaCP60E	NP_001261172.1	Ion_trans	152..371	CDD:278921
		Ion_trans	705..902	CDD:278921
		Ion_trans	1768..2019	CDD:278921	57/262 (22%)
		Na_channel_gate	2009..2063	CDD:240441	3/9 (33%)
		Ion_trans	2085..2320	CDD:278921
		GPHH	2331..2386	CDD:293510
CATSPER2	NP_001269239.1	Ion_trans	178..356	CDD:278921	39/212 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2301
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810