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Protein Alignment Ance-5 and Ace2

DIOPT Version :9

Sequence 1:	NP_573392.2	Gene:	Ance-5 / 37980	FlyBaseID:	FBgn0035076	Length:	628	Species:	Drosophila melanogaster
Sequence 2:	NP_001123985.1	Gene:	Ace2 / 70008	MGIID:	1917258	Length:	805	Species:	Mus musculus

Alignment Length:	658	Identity:	155/658 - (23%)
Similarity:	272/658 - (41%)	Gaps:	97/658 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SLILLLSVTFGIGQSSYELATKQILDRAKDRMRHV--------WSLNRRIFVQLTAKGKSPLGGQ 65
            |.:||..|.....||..|...|..|:........:        |:.|..|..:..
Mouse     5 SWLLLSLVAVTTAQSLTEENAKTFLNNFNQEAEDLSYQSSLASWNYNTNITEENA---------- 59

  Fly    66 VLNSKLEVEAETYRLFY-DLAGNLSVVSVAELNDPLLRRRVQRMAKLQLQGLRPKDYEQAKDLLR 129
               .|:...|..:..|| :.:......|:.|:..|:::|::|.:.:.....|.....:|...:|.
Mouse    60 ---QKMSEAAAKWSAFYEEQSKTAQSFSLQEIQTPIIKRQLQALQQSGSSALSADKNKQLNTILN 121

  Fly   130 QIHNFVNGPLVC----PYEDCSARGSLAMYPQIMNKNMHTKL-YEDLVINWKAWRRAINEKDVAK 189
            .:....:...||    | ::|     |.:.|. :::.|.|.. |...:..|:.||..:.::  .:
Mouse   122 TMSTIYSTGKVCNPKNP-QEC-----LLLEPG-LDEIMATSTDYNSRLWAWEGWRAEVGKQ--LR 177

  Fly   190 NTFIGYVRLLRIAATYNGHVTPSRTWYLNYDTE-----NFQ-----AEMEAVVWEIMPLYRELHA 244
            ..:..||.|....|..|.:......|..:|:.|     |:.     .::|....||.|||..|||
Mouse   178 PLYEEYVVLKNEMARANNYNDYGDYWRGDYEAEGADGYNYNRNQLIEDVERTFAEIKPLYEHLHA 242

  Fly   245 YLRREVQAAYPKADTKSDGAISAPIMDQILSQDW---YPHQFFRTPHQGRQHQLPSVHRRLEEVL 306
            |:||::...||...:.: |.:.|.::..:..:.|   ||   ...|..    |.|::.
Mouse   243 YVRRKLMDTYPSYISPT-GCLPAHLLGDMWGRFWTNLYP---LTVPFA----QKPNID------- 292

  Fly   307 VTPVKIN---------RKAAEFFESLGLMVMPNIFYDRFSRRMNDEEGGAECKSQVYYFPP---- 358
            ||...:|         ::|.:||.|:||   |::....::..|..|.....   :|...|.
Mouse   293 VTDAMMNQGWDAERIFQEAEKFFVSVGL---PHMTQGFWANSMLTEPADGR---KVVCHPTAWDL 351

  Fly   359 ---DVALRYCPKLDYKKMMQIHGTMAELQYHLYKMQLPFGLDTEPCPGFGAAIAETVILASGTPR 420
               |..::.|.|:.....:..|..|..:||.:...:.||.|......||..|:.|.:.|::.||:
Mouse   352 GHGDFRIKMCTKVTMDNFLTAHHEMGHIQYDMAYARQPFLLRNGANEGFHEAVGEIMSLSAATPK 416

  Fly   421 HLHRLHILLNDSLTE-EQSLNRLFRMGVHTLIAVPQYFINDKFLVDVMDGRIGVKDYNCAYWGLQ 484
            ||..:.:|.:|...: |..:|.|.:..:..:..:|..::.:|:...|..|.|..:.:...:|.::
Mouse   417 HLKSIGLLPSDFQEDSETEINFLLKQALTIVGTLPFTYMLEKWRWMVFRGEIPKEQWMKKWWEMK 481

  Fly   485 DKFAGVQPPLQRLNKDFDVDFKFYRGLNPETSNTKKFLAEILGFQFYRSFCLASGQYKPGDPNFP 549
            .:..||..||.......|....|:  ::.:.|..:.:...|..|||..:.|.|: :|     |..
Mouse   482 REIVGVVEPLPHDETYCDPASLFH--VSNDYSFIRYYTRTIYQFQFQEALCQAA-KY-----NGS 538

  Fly   550 LHNCDFYDSKEAGKKIRDMMQLGATRHWRDVMEIATGERKLSGRGILEYFAPLFTWLKERNKQLD 614
            ||.||..:|.|||:|:..|:.||.:..|...:|...|.|.:..:.:|.||.|||.||||:|:...
Mouse   539 LHKCDISNSTEAGQKLLKMLSLGNSEPWTKALENVVGARNMDVKPLLNYFQPLFDWLKEQNRNSF 603

  Fly   615 IEPGWDAD 622
            :  ||:.:
Mouse   604 V--GWNTE 609

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.