Protein Alignment Ance-5 and Ace3

DIOPT Version :9

• Sequence 1: NP_573392.2
• Gene: Ance-5 / 37980
• FlyBaseID: FBgn0035076
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001245166.1
• Gene: Ace3 / 498012
• RGDID: 1561299
• Length: 737
• Species: Rattus norvegicus
• Alignment Length: 608
• Identity: 157/608 - (25%)
• Similarity: 269/608 - (44%)
• Gaps: 55/608 - (9%)

  Fly    25 YELATKQILDRAKDRMRHVWSLNRRIFVQLTAKGKSPLGGQVLNSKLEVEAETYRLFYDLAGNLS 89
            ||...:.:|:   :.|...|:....|..|          .|....:.|||...:.|::.....:
  Rat    45 YEQTARVVLN---ELMEATWNYVTNITKQ----------NQENMLQKEVERSQFMLYFGTRARM- 95

  Fly    90 VVSVAELNDPLLRRRVQRMAKLQLQGLRPKDYEQAKDLLRQIHNFVNGPLVCPYE-DCSARGSLA 153
             ..:....|..::||:.::..:....|..:|:::...||..:........||..| .|     :.
  Rat    96 -FRIDHFQDLDVKRRLSKLRNIDKSALPVEDFQEFNRLLTYMKTAYGRAEVCLDEGPC-----MP 154

  Fly   154 MYPQIMNKNMHTKLYEDLVINWKAWRRAINEKDVAKNTFIGYVRLLRIAATYNGHVTPSRTWYLN 218
            :.|.:......::..::|:..|:.||.||..:  .:..|..||.|...||.|||:......|...
  Rat   155 LEPDLEEIMATSRDQKELLWAWQGWRDAIGRQ--LRPVFEDYVHLSNKAAQYNGYKDMGALWRSK 217

  Fly   219 YDTENFQAEMEAVVWEIMPLYRELHAYLRREVQAAYPKADTKSDGAISAPIMDQILSQDW----- 278
            |:::..:.::|.:..|:.|||..||||:||.:...|........|.|.|.::..:.:|.|
  Rat   218 YESDTLEEDLEQLYKELQPLYLNLHAYVRRSLYRYYGPELIDLRGPIPAHLLGNMWAQSWNNILD 282

  Fly   279 ----YPHQFFRTPHQGRQHQLPSVHRRLEEVLVTPVKINRKAAEFFESLGLMVMPNIFY--DRFS 337
                ||::    |.:.....:.:.|.|       |.|:..:|..||.|:|::..|..|:  ....
  Rat   283 LVLPYPNK----PPEDITKIMKNQHWR-------PEKMFEEANLFFTSMGMLPAPPAFWMKSMME 336

  Fly   338 RRMNDEEGGAECKSQVYYFPPDVALRYCPKLDYKKMMQIHGTMAELQYHLYKMQLPFGLDTEPCP 402
            :.::..|......|..:|...|..::.|.::....::.|...|..:||:|....|.........|
  Rat   337 KPVDGREVECHTSSWNFYRLNDFRVKKCTEVTIGDLLSIFHQMGHIQYYLQCQNLSIIYQEGASP 401

  Fly   403 GFGAAIAETVILASGTPRHLHRLHILLNDSLTEEQSLNRLFRMGVHTLIAVPQYFINDKFLVDVM 467
            .|..|:..|:.|::.:.::|....:|.......|:.:|.|..:.:..:..:|..::.|.|...|.
  Rat   402 AFEEAVGSTITLSAFSHKYLLTRGLLSQQHQDSEEEVNFLLSIALEKIAFIPFGYMIDLFRWKVF 466

  Fly   468 DGRIGVKDYNCAYWGLQDKFAGVQPPLQRLNKDFDVDFKFYRGLNPETSNTKKFLAEILGFQFYR 532
            ||.|....||..:|.|:.|:.|:.||:.|...|||...||:...|  ....:.||:.:|.||.:.
  Rat   467 DGTIQKNAYNQEWWSLRLKYQGLCPPVPRSEDDFDPGAKFHIPAN--MPYIRYFLSLVLQFQLHE 529

  Fly   533 SFCLASGQYKPGDPNFPLHNCDFYDSKEAGKKIRDMMQLGATRHWRDVMEIATGERKLSGRGILE 597
            ..|.|||...      |||.||.|:||.|||.:.|.:::|::|.|::|::..||:..:|.:.:|.
  Rat   530 VLCRASGHVG------PLHRCDIYNSKVAGKILGDFLKVGSSRPWQEVLKEITGKPNISTKALLT 588

  Fly   598 YFAPLFTWLKERN-KQLDIEPGW 619
            ||.||..||...| ||.|| .||
  Rat   589 YFKPLLNWLVTENVKQGDI-LGW 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-5	NP_573392.2	GluZincin	93..610	CDD:301352	138/528 (26%)
Ace3	NP_001245166.1	Peptidase_M2	34..610	CDD:279709	155/606 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166339581
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266227at33208
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950