Protein Alignment Ance-5 and ace2

DIOPT Version :9

• Sequence 1: NP_573392.2
• Gene: Ance-5 / 37980
• FlyBaseID: FBgn0035076
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_005169416.1
• Gene: ace2 / 492331
• ZFINID: ZDB-GENE-041114-6
• Length: 818
• Species: Danio rerio
• Alignment Length: 637
• Identity: 152/637 - (23%)
• Similarity: 281/637 - (44%)
• Gaps: 78/637 - (12%)

  Fly    27 LATKQILDRAKDRMRHVWSLNR------RIFVQLTAKGKSPLGGQVLNSKL-----EVEAETYRL 80
            ||:.......:||.|..  ||:      .|..|.|      |.....|:.:     :.|||.|.:
Zfish    11 LASVACCQTVEDRAREF--LNKFDEEASDIMYQYT------LASWAYNTDISQENADKEAEAYAI 67

  Fly    81 FYDLAGNLSVVS----VAELNDPLLRRRVQRMAKLQLQG---LRPKDYEQAKDLLRQIHNFVNGP 138
            :.:....:|..|    :.:::||:::.::|   |||.:|   |.|....:.::::.::....|..
Zfish    68 WSEYYNKMSEESNAYPIDQISDPIIKMQLQ---KLQDKGSGALSPDKASELRNIMSEMSTIYNTA 129

  Fly   139 LVCPYE---DCSARGSLAMYPQIMNKNMHTKLYEDLVINWKAWRRAINEKDVAKNTFIGYVRLLR 200
            .||..:   ||.     .:.|.:.:....::.|::.:..|:.||.|...|  .:..:..||.|..
Zfish   130 TVCKIDDPTDCQ-----TLEPGLESIMAESRDYDERLHVWEGWRVATGMK--MRPLYEKYVDLKN 187

  Fly   201 IAATYNGHVTPSRTWYLNYDT----------ENFQAEMEAVVWEIMPLYRELHAYLRREVQAAYP 255
            .||..|.:......|..:|:|          :....:...:..||:|||:|||||:|.::|..||
Zfish   188 EAAKLNNYEDHGDYWRGDYETIDDPKYSYSRDQVIEDARRIYKEILPLYKELHAYVRAKLQDVYP 252

  Fly   256 KADTKSDGAISAPIMDQILSQDW---YPHQFFRTPHQGRQHQLPSVHRRLEEVLV----TPVKIN 313
             ....||..:.|.::..:..:.|   ||   ...|:..|    |.:.  :...:|    ..:::.
Zfish   253 -GHIGSDACLPAHLLGDMWGRFWTNLYP---LMIPYPDR----PDID--VSSAMVEQGWDEIRLF 307

  Fly   314 RKAAEFFESLGLMVMPNIFYDRFSRRMNDEEGGAECKSQVYYF--PPDVALRYCPKLDYKKMMQI 376
            ::|.:||.|:.:..|.:.|::. |..:..||....|....:..  ..|..::.|.|::....:.:
Zfish   308 KEAEKFFMSVNMPAMFDNFWNN-SMFIKPEERDVVCHPTAWDMGNRKDFRIKMCTKVNMDDFLTV 371

  Fly   377 HGTMAELQYHLYKMQLPFGLDTEPCPGFGAAIAETVILASGTPRHLHRLHILLNDSLTE-EQSLN 440
            |..|...||.:.....|:.|......||..|:.|.:.|::.||.||..|.:|.:|...: |..:|
Zfish   372 HHEMGHNQYQMAYRNHPYLLRDGANEGFHEAVGEIMSLSAATPSHLQSLGLLPSDFKQDYETDIN 436

  Fly   441 RLFRMGVHTLIAVPQYFINDKFLVDVMDGRIGVKDYNCAYWGLQDKFAGVQPPLQRLNKDFDVDF 505
            .|.:..:..:..:|..::.:::...|...:|...::...:|.::.:..||...:.|.....|...
Zfish   437 FLLKQALTIVGTLPFTYMLEEWRWQVFKAKIPKDEWMQQWWQMKRELVGVAEAVPRDETYCDPPA 501

  Fly   506 KFYRGLNPETSNTKKFLAEILGFQFYRSFCLASGQYKPGDPNFPLHNCDFYDSKEAGKKIRDMMQ 570
            .|:  ::.:.|..:.|...|..|||..:.|.|:|.      ..||:.||..:|.:||.|:|.|::
Zfish   502 LFH--VSGDYSFIRYFTRTIYQFQFQEALCKAAGH------TGPLYKCDITNSTKAGDKLRHMLE 558

  Fly   571 LGATRHWRDVMEIATGERKLSGRGILEYFAPLFTWLKERNKQLDIEPGWDAD 622
            ||.:..|...:|...|..|:..:.:|.||:.|..||||.|::.:..|||:.:
Zfish   559 LGRSMSWTRALEEVAGTTKMDSQPLLHYFSTLMEWLKEENQKNNRVPGWNVN 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-5	NP_573392.2	GluZincin	93..610	CDD:301352	130/542 (24%)
ace2	XP_005169416.1	M2_ACE	27..598	CDD:188999	143/607 (24%)
		Collectrin	630..781	CDD:293564

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3690
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266227at33208
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.920