Protein Alignment Ance-5 and acn-1

DIOPT Version :9

• Sequence 1: NP_573392.2
• Gene: Ance-5 / 37980
• FlyBaseID: FBgn0035076
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: NP_001024453.1
• Gene: acn-1 / 180780
• WormBaseID: WBGene00000039
• Length: 906
• Species: Caenorhabditis elegans
• Alignment Length: 621
• Identity: 128/621 - (20%)
• Similarity: 245/621 - (39%)
• Gaps: 121/621 - (19%)

  Fly    72 EVEAETYRLFYDLAGNLSVV----------------------SVAELNDPLLRRRVQRMAKLQLQ 114
            ||....:|.|.|.:.:|.:.                      .:|.:.|..:.|::..::...:.
 Worm   198 EVALSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTDEKVMRQLGYVSFEGMS 262

  Fly   115 GLRPK---DYEQAKDLLRQIHNFVNGPLVCPYE---DCSARGSLAMYPQIMNKNMHTKLYEDLVI 173
            .|.|.   ||.||:..|.:..   ....:|..:   .|:.:                |:..|.:.
 Worm   263 ALAPSRFADYSQAQAALNRDS---KDSTICDKDVPPPCALQ----------------KIDMDSIF 308

  Fly   174 NWKAWRRAINEKDVAK--NTFIGYV-----------RLLRIA---ATYNGHVTPSRTWYLNYDTE 222
            .        ||||.::  :.::.||           .::.|:   |..||.......|...:|..
 Worm   309 R--------NEKDASRLQHLWVSYVTAIAKSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMS 365

  Fly   223 --------NFQAEMEAVVWEIMPLYRELHAYLRREVQAAYPK-ADTKSDGAISAPIMDQILSQDW 278
                    :...:::.:...|.|.|:.||||:||::...|.. .....||.|.|.:...:...||
 Worm   366 SKVHKAEFDLNKQIDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDW 430

  Fly   279 YPHQFFRTPHQGRQHQLPSVHRRLEEVLVTPVKINRKAAEFFESLGLMVMP------NIFYDRFS 337
            ..|.....|.:.......::.........|..|:...|..:|:|.|...:|      :||...:|
 Worm   431 SAHYEQTKPFEEESETPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWS 495

  Fly   338 RRMNDEEGGA-ECKSQVYYFPPDVALRYCPKLDYKKMMQIHGTMAELQY-HLYKMQ-LPFGLDTE 399
            :.|......| :.::     |.|..::.|.:|......|.|..:.:..| :|||.| |.|  ..:
 Worm   496 KDMICHPAAALDMRA-----PNDFRVKACAQLGEPDFEQAHSLLVQTYYQYLYKDQSLLF--REQ 553

  Fly   400 PCPGFGAAIAETVILASGTPRHLHRLHILLNDSLTEEQS--LNRLFRMGVHTLIAVPQYFINDKF 462
            ..|....|||......|..|.:|:...::.::.|..:.|  :|:|::..:.:...:|.....|.:
 Worm   554 ASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFTIAADNW 618

  Fly   463 LVDVMDGRIGVKDYNCAYWGLQDKFAGVQPPLQRLNKDFDVDFKFYRGLNP-ETSNTKKFLAEIL 526
            ..::.||.:.....|..:|.:::|:.||:.| |..|.. ::|...:..::. .:..|:..::.:|
 Worm   619 RYELFDGTVPKNKLNDRWWEIRNKYEGVRSP-QPYNTS-NLDALIHNSVSQVHSPATRTLISYVL 681

  Fly   527 GFQFYRSFC-----LASGQYKPGDPNFPLHNCDFYDSKEAGKKIRDMMQLGATRHWRDVMEIATG 586
            .||..::.|     |:.|             |..  |::..:|:|:.|:||::..|...:|:.:|
 Worm   682 KFQILKALCPEGTILSEG-------------CIL--SEDTTEKLRETMKLGSSITWLKALEMISG 731

  Fly   587 ERKLSGRGILEYFAPLFTWLKERNKQLDIEPGWDAD 622
            :.:|..:.:|||:.||..||:..|:...:..|||.:
 Worm   732 KGELDAQPLLEYYEPLINWLRNTNEIDQVVVGWDGE 767

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-5	NP_573392.2	GluZincin	93..610	CDD:301352	118/564 (21%)
acn-1	NP_001024453.1	Peptidase_M2	175..764	CDD:279709	125/616 (20%)
		EB	<794..833	CDD:279949

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5260
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	1	1.000	-	-		otm14376
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10514
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960