Protein Alignment Ance-5 and ace2

DIOPT Version :9

• Sequence 1: NP_573392.2
• Gene: Ance-5 / 37980
• FlyBaseID: FBgn0035076
• Length: 628
• Species: Drosophila melanogaster
• Sequence 2: XP_002938293.2
• Gene: ace2 / 100486137
• XenbaseID: XB-GENE-487117
• Length: 862
• Species: Xenopus tropicalis
• Alignment Length: 664
• Identity: 153/664 - (23%)
• Similarity: 286/664 - (43%)
• Gaps: 105/664 - (15%)

  Fly     7 GVSLILLLSVTFGIGQSSYELATKQILDRAKDRMRHV---------------WSLNRRIFVQLTA 56
            |:..:..:.:....|:|      :.:.|:|:|.::..               |..|..| ....|
 Frog     3 GLLWLFCIGLLLATGRS------QSVTDQARDFLKRFEQEAEVLYHQSALAQWEYNTNI-TDENA 60

  Fly    57 KGKSPLGGQVLNSKLEVEAETYRLFYDLAG-NLSVVSVAELNDPLLRRRVQRMAKLQLQGLRPKD 120
            :..|..|.:            :..||..|. |....:...:.||.:..::..:::.....|..:.
 Frog    61 QKMSEAGAK------------WSAFYTNASKNSEAFNKDYITDPSIELQLIFLSEKGSAILPAEK 113

  Fly   121 YEQAKDLLRQIHNFVNGPLVCPYEDCSARGSLAMYP---QIMNKNMHTKLYEDLVINWKAWRRAI 182
            |.:...:|.::....:...||..:  .::..|.:.|   :||.:::.   ||:.:..|:.||...
 Frog   114 YTRLNQVLNEMSTIYSTHAVCKPD--GSKECLPLEPGLDKIMAESID---YEERLWAWEGWRAGA 173

  Fly   183 NEKDVAKNTFIGYVRLLRIAATYNGHVTPSRTWYLNYDT----------ENFQAEMEAVVWEIMP 237
            .:|  .::.:..||.|...||..||:......|..||:|          ::...::|....||:|
 Frog   174 GKK--MRSLYEEYVDLENEAARLNGYNDYGDYWRGNYETLATDMYAYSRDDLIKDVERTYQEILP 236

  Fly   238 LYRELHAYLRREVQAAYPKADTKSDGAISAPIMDQILSQDW---YPHQFFRTPHQGRQHQLPSVH 299
            ||:||||::|..:|..|........|.:.|.::..:..:.|   ||   ...|:..:
 Frog   237 LYKELHAFVRGNLQQVYGSRYISDSGCLPAHLLGDMWGRFWTNLYP---LMVPYPNK-------- 290

  Fly   300 RRLEEVLVTPVKINR--------KAAE-FFESLGLMVMPNIFYDRFSRRMNDEEGGAECKSQVYY 355
               |.:.|||..:.:        |.|| ||:|:.|..:...|::  :..:.:.:.|    .||..
 Frog   291 ---ESIDVTPTMVAQGWTIERMFKEAEIFFKSVDLFALNENFWN--NSMLEEPKDG----RQVVC 346

  Fly   356 FPP-------DVALRYCPKLDYKKMMQIHGTMAELQYHLYKMQLPFGLDTEPCPGFGAAIAETVI 413
            .|.       |..::.|.|::.:..:.:|..:..:||.:...:.||.|......||..|:.|.:.
 Frog   347 HPTAWDLGMNDFRIKMCTKVNMEDFLTVHHELGHIQYDMAYAKQPFMLRDGANEGFHEAVGEIMS 411

  Fly   414 LASGTPRHLHRLHILLNDSLTEEQ--SLNRLFRMGVHTLIAVPQYFINDKFLVDVMDGRIGVKDY 476
            |::.||:||..|. ||:.:..|:|  .:|.|||..:..:..:|..::.:::...|..|.|....:
 Frog   412 LSAATPKHLKHLK-LLDANFVEDQETEINFLFRQALAIVGTLPFTYMLEQWRWKVFRGEIPKDQW 475

  Fly   477 NCAYWGLQDKFAGVQPPLQRLNKDFDVDFKFYRGLNPETSNTKKFLAEILGFQFYRSFCLASGQY 541
            ...:|.::.:..||..|:.......|....|:  ::.:.|..:.:...|..|||..:.|.|:|..
 Frog   476 MKTWWQMKRELVGVVEPVPHDETYCDPPALFH--VSNDYSFIRYYTRTIYQFQFQDALCKAAGHV 538

  Fly   542 KPGDPNFPLHNCDFYDSKEAGKKIRDMMQLGATRHWRDVMEIATGERKLSGRGILEYFAPLFTWL 606
            .      |||.||..:|||||.|:|.|::||..:.|.:.::..||..|:..:.:|:||.|||.||
 Frog   539 G------PLHTCDITNSKEAGAKLRAMLELGKAKSWTEALQSITGGVKMDSQPLLKYFEPLFVWL 597

  Fly   607 KERNKQLDIEPGWD 620
            ::.|::...:..|:
 Frog   598 QKNNEENRRQSTWN 611

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ance-5	NP_573392.2	GluZincin	93..610	CDD:301352	135/550 (25%)
ace2	XP_002938293.2	Peptidase_M2	23..610	CDD:396123	149/635 (23%)
		Collectrin	622..772	CDD:407175

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D266227at33208
OrthoFinder	1	1.000	-	-		FOG0000442
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010