DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NKAIN and nkain1

DIOPT Version :9

Sequence 1:	NP_001246506.1	Gene:	NKAIN / 37979	FlyBaseID:	FBgn0085442	Length:	658	Species:	Drosophila melanogaster
Sequence 2:	NP_956839.1	Gene:	nkain1 / 393517	ZFINID:	ZDB-GENE-040426-1472	Length:	207	Species:	Danio rerio

Alignment Length:	212	Identity:	88/212 - (41%)
Similarity:	121/212 - (57%)	Gaps:	19/212 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSCS--CTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKY 63
            ||.|.  ||    |:.||.||::..::||||||:||.|||||.||.||:.:|.|.:|....|.:|
Zfish     1 MGRCDGRCT----LVVICCLQLVAALQRQVFDFMGYQWAPILANFLHIMAVILGVFGTVQVRSRY 61

  Fly    64 IITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLGTGSV--SWFEANGYGCKPTYNMAADDT 126
            :|.|.:|..:|:|||:|:|||||.||.|::|.|.|.....|:  ||:..||.||..|  ...|..
Zfish    62 LILYAVWLVVWVGWNSFIICFYLEVGHLSQDRDFLMTFNTSLHRSWWMENGPGCLVT--PVPDSP 124

  Fly   127 FRPQRPE--RVEGCLLDYPLVEITHSGVQCALALLGILGAILISCIFLDEDDRFDFMNG----DA 185
            ..||...  .|.||||||..:|:..|.:|..|||.|.:.|..:|....|::|.|||.:|    :.
Zfish   125 LAPQDHHVITVSGCLLDYQYIEVVSSALQVFLALFGFVYACYVSKYSPDDEDSFDFFDGLGSYNY 189

  Fly   186 KSPQ---HTVVHPMYVS 199
            :.||   ...:.|:|.:
Zfish   190 QPPQKISQLQLRPLYTT 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NKAIN	NP_001246506.1	NKAIN	12..199	CDD:283329	83/197 (42%)
nkain1	NP_956839.1	NKAIN	10..206	CDD:283329	83/197 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573909
Domainoid	1	1.000	174	1.000	Domainoid score	I3617
eggNOG	1	0.900	-	-		E1_KOG4556
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001076
OrthoInspector	1	1.000	-	-		otm24570
orthoMCL	1	0.900	-	-		OOG6_106588
Panther	1	1.100	-	-	O	PTHR13084
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X730
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	11	10.700