DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NKAIN and NKAIN2

DIOPT Version :9

Sequence 1:	NP_001246506.1	Gene:	NKAIN / 37979	FlyBaseID:	FBgn0085442	Length:	658	Species:	Drosophila melanogaster
Sequence 2:	XP_011533803.1	Gene:	NKAIN2 / 154215	HGNCID:	16443	Length:	213	Species:	Homo sapiens

Alignment Length:	212	Identity:	92/212 - (43%)
Similarity:	129/212 - (60%)	Gaps:	20/212 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSCS--CTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKY 63
            ||.||  ||    |:.||.:|::.::|||:||||||.|||||.||.||:.:|.|.:|...:|.:|
Human     1 MGYCSGRCT----LIFICGMQLVCVLERQIFDFLGYQWAPILANFVHIIIVILGLFGTIQYRPRY 61

  Fly    64 IITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLGTGSV--SWFEANGYGCKPTYNMAADDT 126
            |..|.:|..||:.||.|:|||||..|.|::::||:.....|:  ||:..||.||..|....|.|
Human    62 ITGYAVWLVLWVTWNVFVICFYLEAGDLSKETDLILTFNISMHRSWWMENGPGCTVTSVTPAPD- 125

  Fly   127 FRPQ--RPERVEGCLLDYPLVEITHSGVQCALALLG-ILGAILISCIFLDEDDRFDFMNG-DA-- 185
            :.|:  |...|.||||:|..:|:.||.:|..|||.| |....::.|| .:|:|.|||:.| |:
Human   126 WAPEDHRYITVSGCLLEYQYIEVAHSSLQIVLALAGFIYACYVVKCI-TEEEDSFDFIGGFDSYG 189

  Fly   186 -KSPQ---HTVVHPMYV 198
             :.||   |..:.|||:
Human   190 YQGPQKTSHLQLQPMYM 206

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NKAIN	NP_001246506.1	NKAIN	12..199	CDD:283329	86/199 (43%)
NKAIN2	XP_011533803.1	NKAIN	10..206	CDD:398973	85/197 (43%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141037
Domainoid	1	1.000	178	1.000	Domainoid score	I3564
eggNOG	1	0.900	-	-		E1_KOG4556
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001076
OrthoInspector	1	1.000	-	-		otm41902
orthoMCL	1	0.900	-	-		OOG6_106588
Panther	1	1.100	-	-	O	PTHR13084
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4688
SonicParanoid	1	1.000	-	-		X730
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	11	10.730