DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NKAIN and nkain2

DIOPT Version :9

Sequence 1:	NP_001246506.1	Gene:	NKAIN / 37979	FlyBaseID:	FBgn0085442	Length:	658	Species:	Drosophila melanogaster
Sequence 2:	NP_001338635.1	Gene:	nkain2 / 110438188	ZFINID:	ZDB-GENE-041014-77	Length:	208	Species:	Danio rerio

Alignment Length:	215	Identity:	94/215 - (43%)
Similarity:	130/215 - (60%)	Gaps:	24/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSCS--CTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKY 63
            ||.||  ||    |..||.:|:|:|:|||:||||||.|||||.||.||:.:|.|.:|...||.:|
Zfish     1 MGCCSGRCT----LAFICGMQLISILERQIFDFLGYQWAPILTNFIHIITVILGLFGTVQFRPRY 61

  Fly    64 IITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLGTGSV--SWFEANGYGCK-----PTYNM 121
            :..|.:|..||:.||.|:|||||.||.|::|:||:.....|:  ||:..||.||:     |..:.
Zfish    62 VTGYAVWLVLWVAWNVFIICFYLEVGDLSKDTDLIMTFNISMHRSWWMENGPGCRVTPVTPPPSW 126

  Fly   122 AADDTFRPQRPERVEGCLLDYPLVEITHSGVQCALALLGILGAILISCIFLDEDDRFDFMNG-DA 185
            |.:|    .|...:.||||:|..||:.||.:|..|||.|.:.|..:..:..:|:|.|||:.| |:
Zfish   127 APED----HRYISIAGCLLEYQFVEVAHSSLQIILALAGFIYACYVVKLISEEEDSFDFIGGFDS 187

  Fly   186 ---KSPQ---HTVVHPMYVS 199
               :.||   |..:.|||:|
Zfish   188 YGYQGPQKTSHLQLQPMYMS 207

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NKAIN	NP_001246506.1	NKAIN	12..199	CDD:283329	87/200 (44%)
nkain2	NP_001338635.1	NKAIN	10..207	CDD:310324	87/200 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573910
Domainoid	1	1.000	174	1.000	Domainoid score	I3617
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001076
OrthoInspector	1	1.000	-	-		otm24570
orthoMCL	1	0.900	-	-		OOG6_106588
Panther	1	1.100	-	-	O	PTHR13084
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X730
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.840