DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment NKAIN and nkain4

DIOPT Version :9

Sequence 1:	NP_001246506.1	Gene:	NKAIN / 37979	FlyBaseID:	FBgn0085442	Length:	658	Species:	Drosophila melanogaster
Sequence 2:	NP_001107118.1	Gene:	nkain4 / 100002876	ZFINID:	ZDB-GENE-080204-60	Length:	208	Species:	Danio rerio

Alignment Length:	215	Identity:	90/215 - (41%)
Similarity:	124/215 - (57%)	Gaps:	15/215 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MGSCS--CTRRHFLLSICFLQVITIIERQVFDFLGYMWAPILVNFFHILFIIFGFYGAYHFRVKY 63
            ||.||  ||    |:.:|..|::..:||||||||||.|||||.||||||.:|.|.:|...:|.:|
Zfish     1 MGCCSGRCT----LIFLCTFQLMVALERQVFDFLGYQWAPILANFFHILVVILGLFGTIQYRPRY 61

  Fly    64 IITYLIWNFLWIGWNTFLICFYLNVGQLNRDSDLLNLG-TGSVSWFEANGYGC----KPTYNMAA 123
            |:.|.:|..||:.||.|:|||||.||.|::|||||... :...||:..:|.||    .|......
Zfish    62 IVVYTVWTALWVAWNVFVICFYLEVGGLSKDSDLLTFNISAHHSWWSEHGPGCIRREIPASGERG 126

  Fly   124 DDTFRPQRPERVEGCLLDYPLVEITHSGVQCALALLGILGAILISCIFLDEDDRFDFMNGDAKSP 188
            .||   |....:.||||:|..:|:.|||.|..::|||.:.|..:..:..:|:|.|||:.|....|
Zfish   127 ADT---QSYISIMGCLLEYQYIEVLHSGCQILISLLGFIYACYVISVITEEEDSFDFIGGFDPFP 188

  Fly   189 -QHTVVHPMYVSYTSIPTTS 207
             .|....|.::....:|.:|
Zfish   189 LYHVNEKPSHLLLKPVPQSS 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
NKAIN	NP_001246506.1	NKAIN	12..199	CDD:283329	82/192 (43%)
nkain4	NP_001107118.1	NKAIN	10..203	CDD:283329	82/195 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170573908
Domainoid	1	1.000	174	1.000	Domainoid score	I3617
eggNOG	1	0.900	-	-		E1_KOG4556
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001076
OrthoInspector	1	1.000	-	-		otm24570
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13084
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4984
SonicParanoid	1	1.000	-	-		X730
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	10	9.830