DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Atf-2 and Atf7

DIOPT Version :9

Sequence 1:	NP_001033973.1	Gene:	Atf-2 / 37978	FlyBaseID:	FBgn0265193	Length:	381	Species:	Drosophila melanogaster
Sequence 2:	NP_001101585.1	Gene:	Atf7 / 315333	RGDID:	1304940	Length:	485	Species:	Rattus norvegicus

Alignment Length:	438	Identity:	105/438 - (23%)
Similarity:	161/438 - (36%)	Gaps:	156/438 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 GD---FETKSPEGDVSCYQNFRAQTEHVS-------LDISLG-QKSDTLFAADQTPTPTRLIKNC 69
            ||   |...:|    .|.|.| ...:|::       :.:..| .::|::..|||||||||.:|||
  Rat     2 GDDRPFVCSAP----GCGQRF-TNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNC 61

  Fly    70 DEVGLFEDLQHVNPFDIGFQQAA---ERNVSGT--------PSRPEARPNDGESLH---TPQVYP 120
            :|||||.:|  .:.|:..|::|:   |:..|..        ||.|:.:..:.|.:.   :|...|
  Rat    62 EEVGLFNEL--ASSFEHEFKKASDDDEKKASSAAGPLDMSLPSTPDIKVKEEEPVEVDSSPPDSP 124

  Fly   121 VEA--------------PTVVSVPSENQVPQSVSCGDMDVD---QLLATTVTSPSKASQDGP--- 165
            ...              |.|:|.|:    |..|..|.:.:.   ..|..|:.||:......|
  Rat   125 ASCPCSPPLKDKEVATKPVVISTPT----PTIVRPGSLPLHLGYDPLHPTLPSPTSVITQAPPSN 185

  Fly   166 ---------------------------PPLQLIQPQVLTWVLPAQSVP----ISIATVDCNRNRV 199
                                       ||:|:  |.|::...|...||    |....|: |...:
  Rat   186 RQIGSPTGSLPLVMHLANGQTMPMLPGPPVQM--PSVISLARPVSMVPNIPGIPGPPVN-NSGSI 247

  Fly   200 KPTGAIHPFILPKPTAKELNKT-----------------------SKRPE--PILVSCNPPNNEP 239
            .|:|  ||  :|......|..|                       :.|||  .||:. :|....|
  Rat   248 SPSG--HP--MPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQNQILIQ-HPDAPSP 307

  Fly   240 SSASLTPTSQLPIKERLKAIIHSNNNRRSFSTPPKAAKAKDRSRDED-------CMERRRAAASR 297
            :...::|....|          |...||.            |:.|||       .:||.||||||
  Rat   308 AQPQVSPAQPTP----------STGGRRR------------RTVDEDPDERRQRFLERNRAAASR 350

  Fly   298 YRNK-------MRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHR 338
            .|.|       :..:.::|..||.||..|...|...:::|::.|..|:
  Rat   351 CRQKRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHK 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Atf-2	NP_001033973.1	Cnn_1N	<300..336	CDD:285263	10/42 (24%)
Atf7	NP_001101585.1	C2H2 Zn finger	9..31	CDD:275368	5/26 (19%)
		GCN4_cent	47..84	CDD:213399	21/38 (55%)
		bZIP_ATF2	336..396	CDD:269835	19/59 (32%)
		coiled coil	336..396	CDD:269835	19/59 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	63	1.000	Domainoid score	I9992
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5046
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415378at33208
OrthoFinder	1	1.000	-	-		FOG0001072
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19304
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	6.160