| Sequence 1: | NP_001033973.1 | Gene: | Atf-2 / 37978 | FlyBaseID: | FBgn0265193 | Length: | 381 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001243019.1 | Gene: | ATF2 / 1386 | HGNCID: | 784 | Length: | 505 | Species: | Homo sapiens |
| Alignment Length: | 461 | Identity: | 114/461 - (24%) |
|---|---|---|---|
| Similarity: | 185/461 - (40%) | Gaps: | 131/461 - (28%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 29 CYQNFRAQTEHVS-------LDISLG-QKSDTLFAADQTPTPTRLIKNCDEVGLFEDLQHVNPFD 85
Fly 86 IGFQQAAERNVSGTPSRPEARPNDGESLHTPQV-YPVEAPTVVSVPSENQV---PQSVSCGDMDV 146
Fly 147 DQLLATTVTSPSKASQDGPPPLQLIQPQVL-----TWVLPAQSVP----ISIATVDCNRNR-VKP 201
Fly 202 TGAIHPFILPKPTAKELNKTSKRPEPILVSCNPPN-NEPSSASLT--------------PTSQLP 251
Fly 252 I----KERLKAII---------------HSNNNRRSFS------------------------TPP 273
Fly 274 KAAKAKDRSR---DED-------CMERRRAAASRYRNK-------MRNEHKDLIKQNAQLQQENQ 321
Fly 322 ELHERISRLEKELQQHRS------------HSSLAGVVADQLRIPPSSIHLLINVPNVLVPSSAS 374
Fly 375 NASAAK 380 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Atf-2 | NP_001033973.1 | Cnn_1N | <300..336 | CDD:285263 | 11/42 (26%) |
| ATF2 | NP_001243019.1 | Nuclear export signal 1 (N-NES) | 1..7 | ||
| C2H2 Zn finger | 27..49 | CDD:275370 | 4/17 (24%) | ||
| GCN4_cent | 65..102 | CDD:213399 | 22/38 (58%) | ||
| Herpes_BLLF1 | <90..342 | CDD:282904 | 57/270 (21%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 125..155 | 7/31 (23%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 259..373 | 26/113 (23%) | |||
| Essential for its histone acetyltransferase activity | 296..299 | 0/2 (0%) | |||
| bZIP_ATF2 | 354..414 | CDD:269835 | 20/59 (34%) | ||
| Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 | 354..374 | 10/19 (53%) | |||
| coiled coil | 355..406 | CDD:269835 | 18/50 (36%) | ||
| Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978 | 380..408 | 8/27 (30%) | |||
| Nuclear export signal 2 (C-NES) | 405..414 | 2/8 (25%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 425..472 | 8/46 (17%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 60 | 1.000 | Domainoid score | I10581 |
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 84 | 1.000 | Inparanoid score | I5177 |
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D415378at33208 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0001072 | |
| OrthoInspector | 1 | 1.000 | - | - | oto89759 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR19304 |
| Phylome | 0 | 0.000 | Not matched by this tool. | |||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R103 |
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 8 | 8.190 | |||||