Protein Alignment Atf-2 and CREB1

DIOPT Version :9

• Sequence 1: NP_001033973.1
• Gene: Atf-2 / 37978
• FlyBaseID: FBgn0265193
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001358355.1
• Gene: CREB1 / 1385
• HGNCID: 2345
• Length: 341
• Species: Homo sapiens
• Alignment Length: 370
• Identity: 79/370 - (21%)
• Similarity: 123/370 - (33%)
• Gaps: 105/370 - (28%)

  Fly    10 LASVSFGDFETKSPEGDVSCYQNFRAQTEHVSLDISLGQKSDTLFAADQTPTPTRLIKNCDEV-G 73
            ||.||.......|....|:..|....||..|...|...|.|     ..|:|....:..:|.:: .
Human    36 LAQVSMPAAHATSSAPTVTLVQLPNGQTVQVHGVIQAAQPS-----VIQSPQVQTVQSSCKDLKR 95

  Fly    74 LFEDLQHVNPFDIGFQQAAERNVSGTPSRPE---ARP------ND----------------GESL 113
            ||...|.....:....|.:..:|:.:..|.|   .||      ||                .|..
Human    96 LFSGTQISTIAESEDSQESVDSVTDSQKRREILSRRPSYRKILNDLSSDAPGVPRIEEEKSEEET 160

  Fly   114 HTPQVYPVEAPTVVSVPSENQ--------VPQSVSCGDMDVDQLLATTVTSPSKASQDGPPPLQL 170
            ..|.:..|..||.:...|..|        ..|..:.|...|..|...|:|: :.|:|.|...||.
Human   161 SAPAITTVTVPTPIYQTSSGQYIAITQGGAIQLANNGTDGVQGLQTLTMTN-AAATQPGTTILQY 224

  Fly   171 IQ----PQVLTWVLPAQSVPISIATVDCNRNRVK--PTGAIHPFILPKPTAKELNKTSKRPEPIL 229
            .|    .|:|   :|:..|.:..|:.|....:::  ||..|.|                   .::
Human   225 AQTTDGQQIL---VPSNQVVVQAASGDVQTYQIRTAPTSTIAP-------------------GVV 267

  Fly   230 VSCNPPNNEPSSASLTPTSQLPIKERLKAIIHSNNNRRSFSTPPKAAKAKDRSRDEDCMERRRAA 294
            ::.:|                                   :.|.:.|:...|.|:...| :.|.|
Human   268 MASSP-----------------------------------ALPTQPAEEAARKREVRLM-KNREA 296

  Fly   295 ASRYRNKMRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHRS 339
            |...|.|.:...|.|..:.|.|:.:|:.|.|.:..| |:|..|:|
Human   297 ARECRRKKKEYVKCLENRVAVLENQNKTLIEELKAL-KDLYCHKS 340

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf-2	NP_001033973.1	Cnn_1N	<300..336	CDD:285263	11/35 (31%)
CREB1	NP_001358355.1	pKID	113..151	CDD:396650	7/37 (19%)
		bZIP_CREB1	285..339	CDD:269838	17/55 (31%)
		coiled coil	286..337	CDD:269838	17/52 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R103
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.030