Protein Alignment Atf-2 and Atf2

DIOPT Version :10

• Sequence 1: NP_001033973.1
• Gene: Atf-2 / 37978
• FlyBaseID: FBgn0265193
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001020264.1
• Gene: Atf2 / 11909
• MGIID: 109349
• Length: 487
• Species: Mus musculus
• Alignment Length: 461
• Identity: 115/461 - (24%)
• Similarity: 185/461 - (40%)
• Gaps: 131/461 - (28%)

  Fly    29 CYQNFRAQTEHVS-------LDISLG-QKSDTLFAADQTPTPTRLIKNCDEVGLFEDLQHVNPFD 85
            |.|.| ...:|::       :.:..| .::|::..|||||||||.:|||:|||||.:|  .:||:
Mouse    14 CGQRF-TNEDHLAVHKHKHEMTLKFGPARNDSVIVADQTPTPTRFLKNCEEVGLFNEL--ASPFE 75

  Fly    86 IGFQQAAERNVSGTPSRPEARPNDGESLHTPQV-YPVEAPTVVSVPSENQV---PQSVSCGDMDV 146
            ..|::|:|.::       :..|.|...|.||.: ..:|.|:||....::..   |:|.:..:.:|
Mouse    76 NEFKKASEDDI-------KKMPLDLSPLATPIIRSKIEEPSVVETTHQDSPLPHPESTTSDEKEV 133

  Fly   147 DQLLATTVTSPSKASQDGPPPLQLIQPQVL-----TWVLPAQSVP----ISIATVDCNRNR-VKP 201
            .  ||.|....|...:  |..||:  |.||     :.|:..|:||    .::.|...:.|| :.|
Mouse   134 P--LAQTAQPTSAIVR--PASLQV--PNVLLTSSDSSVIIQQAVPSPTSSTVITQAPSSNRPIVP 192

  Fly   202 TGAIHPFILPKPTAKELNKTSKRPEPILVSCNPPN-NEPSSASLT--------------PTSQLP 251
            .....|.:|..|..:.:      |..|..|....| :.|::..|.              |:|..|
Mouse   193 VPGPFPLLLHLPNGQTM------PVAIPASITSSNVHVPAAVPLVRPVTMVPSVPGIPGPSSPQP 251

  Fly   252 I----KERLKAII---------------HSNNNRRSFS------------------------TPP 273
            :    |.||||.:               |.:...|:.|                        |.|
Mouse   252 VQSEAKMRLKAALTQQHPPVTNGDTVKGHGSGLVRTQSEESRPQSLQQPATSTTETPASPAHTTP 316

  Fly   274 KAAKAKDRSR---DED-------CMERRRAAASRYRNK-------MRNEHKDLIKQNAQLQQENQ 321
            :......|.|   :||       .:||.||||||.|.|       :..:.:||...|.|||.|..
Mouse   317 QTQNTSGRRRRAANEDPDEKRRKFLERNRAAASRCRQKRKVWVQSLEKKAEDLSSLNGQLQSEVT 381

  Fly   322 ELHERISRLEKELQQHRS------------HSSLAGVVADQLRIPPSSIHLLINVPNVLVPSSAS 374
            .|...:::|::.|..|:.            |::.....::.|.:|.|.....|...:|...:..|
Mouse   382 LLRNEVAQLKQLLLAHKDCPVTAMQKKSGYHTADKDDSSEDLSVPSSPHTEAIQHSSVSTSNGVS 446

  Fly   375 NASAAK 380
            :.|.|:
Mouse   447 STSKAE 452

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf-2	NP_001033973.1	Jnk-SapK_ap_N	<302..343	CDD:462875	12/52 (23%)
Atf2	NP_001020264.1	C2H2 Zn finger	9..31	CDD:275370	4/17 (24%)
		GCN4_cent	47..84	CDD:213399	22/38 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	106..137		8/32 (25%)
		PRK12323	<184..>312	CDD:481241	23/133 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	241..355		26/113 (23%)
		Essential for its histone acetyltransferase activity. /evidence=ECO:0000250	278..281		0/2 (0%)
		bZIP_ATF2	336..396	CDD:269835	20/59 (34%)
		coiled coil	336..396	CDD:269835	20/59 (34%)
		Basic motif. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	336..356		10/19 (53%)
		Leucine-zipper. /evidence=ECO:0000255|PROSITE-ProRule:PRU00978	362..390		8/27 (30%)
		Nuclear export signal. /evidence=ECO:0000250	387..396		2/8 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	407..453		9/46 (20%)