Protein Alignment Atf-2 and ATF7-NPFF

DIOPT Version :10

• Sequence 1: NP_001033973.1
• Gene: Atf-2 / 37978
• FlyBaseID: FBgn0265193
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001353488.1
• Gene: ATF7-NPFF / 114108587
• HGNCID: 55073
• Length: 463
• Species: Homo sapiens
• Alignment Length: 454
• Identity: 113/454 - (24%)
• Similarity: 179/454 - (39%)
• Gaps: 146/454 - (32%)

  Fly    16 GD---FETKSPEGDVSCYQNFRAQTEHVS-------LDISLG-QKSDTLFAADQTPTPTRLIKNC 69
            ||   |...:|    .|.|.| ...:|::       :.:..| .::|::..|||||||||.:|||
Human     2 GDDRPFVCNAP----GCGQRF-TNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNC 61

  Fly    70 DEVGLFEDLQHVNPFDIGFQQAAERNVS---------GTPSRPEARPNDGESLH---TPQVYPVE 122
            :|||||.:|  .:.|:..|::||:.:..         ..||.|:.:..:.|.:.   :|...|..
Human    62 EEVGLFNEL--ASSFEHEFKKAADEDEKKAAAGPLDMSLPSTPDIKIKEEEPVEVDSSPPDSPAS 124

  Fly   123 APTVVSVPSENQVPQSVSCGDMDVDQLLAT---TVTSPSKASQDGPPPLQL----IQPQVLTWVL 180
            :|....:..:...|:.|         |::|   |:..|      |..||.|    :.|     .|
Human   125 SPCSPPLKEKEVTPKPV---------LISTPTPTIVRP------GSLPLHLGYDPLHP-----TL 169

  Fly   181 PAQSVPISIAT--VDCNRNRVKPTGAIHPF-----------ILPKPTAKELNKTS-KRPEPILVS 231
            |:   |.|:.|  ...||....|||:: |.           :||.|..:..:..| .||..::.:
Human   170 PS---PTSVITQAPPSNRQMGSPTGSL-PLVMHLANGQTMPVLPGPPVQMPSVISLARPVSMVPN 230

  Fly   232 C----NPPNNEPSSASLTPTSQLPI----KERLKA------------------------------ 258
            .    .||.|  ||.|::|:.. ||    |.||||
Human   231 IPGIPGPPVN--SSGSISPSGH-PIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMVTARPEQ 292

  Fly   259 --IIHSNNNRRSFSTP--------PKAAKAKDRSRDED-------CMERRRAAASRYRNK----- 301
              |:..:.:..|.:.|        |.....:.|:.|||       .:||.||||||.|.|
Human   293 SQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQKRKLWV 357

  Fly   302 --MRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHRS------HSSLAGVVADQLRIPPSS 357
              :..:.::|..||.||..|...|...:::|::.|..|:.      .....|.:..:.|.||::
Human   358 SSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHKDCPVTALQKKTQGYLGGRQRTPPTT 421

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf-2	NP_001033973.1	Jnk-SapK_ap_N	<302..343	CDD:462875	10/46 (22%)
ATF7-NPFF	NP_001353488.1	C2H2 Zn finger	9..31	CDD:275370	5/26 (19%)
		GCN4_cent	47..84	CDD:213399	22/38 (58%)
		bZIP_ATF2	334..394	CDD:269835	19/59 (32%)
		coiled coil	334..394	CDD:269835	19/59 (32%)