Protein Alignment Atf-2 and ATF7

DIOPT Version :9

• Sequence 1: NP_001033973.1
• Gene: Atf-2 / 37978
• FlyBaseID: FBgn0265193
• Length: 381
• Species: Drosophila melanogaster
• Sequence 2: NP_001353484.1
• Gene: ATF7 / 11016
• HGNCID: 792
• Length: 494
• Species: Homo sapiens
• Alignment Length: 435
• Identity: 113/435 - (25%)
• Similarity: 171/435 - (39%)
• Gaps: 141/435 - (32%)

  Fly    16 GD---FETKSPEGDVSCYQNFRAQTEHVS-------LDISLG-QKSDTLFAADQTPTPTRLIKNC 69
            ||   |...:|    .|.|.| ...:|::       :.:..| .::|::..|||||||||.:|||
Human     2 GDDRPFVCNAP----GCGQRF-TNEDHLAVHKHKHEMTLKFGPARTDSVIIADQTPTPTRFLKNC 61

  Fly    70 DEVGLFEDLQHVNPFDIGFQQAAERNVSGTPSRPEAR-------PNDGESLHTPQV-----YPVE 122
            :|||||.:|  .:.|:..|::||:.:.....||..|:       |.|.....||.:     .|||
Human    62 EEVGLFNEL--ASSFEHEFKKAADEDEKKARSRTVAKKLVAAAGPLDMSLPSTPDIKIKEEEPVE 124

  Fly   123 APTVVSVPSENQVPQSVSCGDMDVDQLLATTVTSPSKASQDGPPPL-------QLIQPQVLTWVL 180
               |.|.|.::  |.|..|             :.|.|..:..|.|:       .:::|..|...|
Human   125 ---VDSSPPDS--PASSPC-------------SPPLKEKEVTPKPVLISTPTPTIVRPGSLPLHL 171

  Fly   181 ------PAQSVPISIAT--VDCNRNRVKPTGAIHPF-----------ILPKPTAKELNKTS-KRP 225
                  |....|.|:.|  ...||....|||:: |.           :||.|..:..:..| .||
Human   172 GYDPLHPTLPSPTSVITQAPPSNRQMGSPTGSL-PLVMHLANGQTMPVLPGPPVQMPSVISLARP 235

  Fly   226 EPILVSC----NPPNNEPSSASLTPTSQLPI----KERLKA------------------------ 258
            ..::.:.    .||.|  ||.|::|:.. ||    |.||||
Human   236 VSMVPNIPGIPGPPVN--SSGSISPSGH-PIPSEAKMRLKATLTHQVSSINGGCGMVVGTASTMV 297

  Fly   259 --------IIHSNNNRRSFSTP--------PKAAKAKDRSRDED-------CMERRRAAASRYRN 300
                    |:..:.:..|.:.|        |.....:.|:.|||       .:||.||||||.|.
Human   298 TARPEQSQILIQHPDAPSPAQPQVSPAQPTPSTGGRRRRTVDEDPDERRQRFLERNRAAASRCRQ 362

  Fly   301 K-------MRNEHKDLIKQNAQLQQENQELHERISRLEKELQQHR 338
            |       :..:.::|..||.||..|...|...:::|::.|..|:
Human   363 KRKLWVSSLEKKAEELTSQNIQLSNEVTLLRNEVAQLKQLLLAHK 407

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Atf-2	NP_001033973.1	Cnn_1N	<300..336	CDD:285263	10/42 (24%)
ATF7	NP_001353484.1	C2H2 Zn finger	9..31	CDD:275370	5/26 (19%)
		GCN4_cent	47..84	CDD:213399	22/38 (58%)
		bZIP_ATF2	345..405	CDD:269835	19/59 (32%)
		coiled coil	345..405	CDD:269835	19/59 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	60	1.000	Domainoid score	I10581
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	84	1.000	Inparanoid score	I5177
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D415378at33208
OrthoFinder	1	1.000	-	-		FOG0001072
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19304
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R103
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	7	7.190