Protein Alignment CG3650 and PRSS48

DIOPT Version :10

• Sequence 1: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_001340540.1
• Gene: PRSS48 / 345062
• HGNCID: 24635
• Length: 346
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 79/274 - (28%)
• Similarity: 128/274 - (46%)
• Gaps: 54/274 - (19%)

  Fly    13 LLLGLA-SGQ--IQPRIVGGTTTTLSAVGG---FVVNLRYDGTFYCGGSLVTSSHVVTAAHCLK- 70
            ||||:: .||  ...|:|||.    .|..|   :.|:|.:|..|.||||||:...::|||||::
Human    12 LLLGISVCGQPVYSSRVVGGQ----DAAAGRWPWQVSLHFDHNFICGGSLVSERLILTAAHCIQP 72

  Fly    71 GYQASRITVQGGVSKLSQSGVVRRVARYFI------PNGFSSSSLNWDVGVIRLQSALTGSGITT 129
            .:.....||..|...:..|   |:..:|::      |....:::   ||.:::|.|.:|.:. ..
Human    73 TWTTFSYTVWLGSITVGDS---RKRVKYYVSKIVIHPKYQDTTA---DVALLKLSSQVTFTS-AI 130

  Fly   130 IPLC------QVQWNPGNYMRVSGWGTTRYGNSSP-SNQLRTVRIQLIRKKVCQRAYQG------ 181
            :|:|      |:...|  :..|:|||..:..:... .:.|:...:.:|.::.|::.|..
Human   131 LPICLPSVTKQLAIPP--FCWVTGWGKVKESSDRDYHSALQEAEVPIIDRQACEQLYNPIGIFLP 193

  Fly   182 --RDTLTASTFCA--RTGGKDSCSGDSGG-------GVIFKNQLCGIVSWGLGCANAQYPGVYTS 235
              ...:.....||  ....||||.|||||       ||..:.   |:|||||.|..: .|||||:
Human   194 ALEPVIKEDKICAGDTQNMKDSCKGDSGGPLSCHIDGVWIQT---GVVSWGLECGKS-LPGVYTN 254

  Fly   236 VHRVRSFILRSIKK 249
            |...:.:|..:|.:
Human   255 VIYYQKWINATISR 268

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	71/251 (28%)
PRSS48	NP_001340540.1	Tryp_SPc	28..265	CDD:238113	71/253 (28%)