Protein Alignment CG3650 and PRSS53

DIOPT Version :10

• Sequence 1: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: XP_011544118.1
• Gene: PRSS53 / 339105
• HGNCID: 34407
• Length: 623
• Species: Homo sapiens
• Alignment Length: 318
• Identity: 74/318 - (23%)
• Similarity: 111/318 - (34%)
• Gaps: 99/318 - (31%)

  Fly     2 WRPLFLLQ-LTQLLLGLASGQI--------QPRIVGGTTTTLSAVGG---FVVNLRYDGTFYCGG 54
            |.|:.|:. .|.|:.||.:.|.        .|:...|.|     |.|   :..::|..|...|.|
Human     5 WGPVLLIAGATVLMEGLQAAQRACGQRGPGPPKPQEGNT-----VPGEWPWQASVRRQGAHICSG 64

  Fly    55 SLVTSSHVVTAAHCLKGYQASRI----TVQGGVSK--LSQSGVVRRVARYFIPNGFSSSSLNWDV 113
            |||..:.|:|||||.:...|:.:    .|.|.:.:  ||.......||...:|..::..|...|:
Human    65 SLVADTWVLTAAHCFEKAAATELNSWSVVLGSLQREGLSPGAEEVGVAALQLPRAYNHYSQGSDL 129

  Fly   114 GVIRLQSALTGSGITTIPLCQVQ-----------WNPGNYMRVSG---WGTTRYGNS-------- 156
            .:::|....|.:     |||..|           |..|.....|.   |...:.|.:
Human   130 ALLQLAHPTTHT-----PLCLPQPAHRFPFGASCWATGWDQDTSDGKCWPRLKLGEALCLPSVTV 189

  Fly   157 -------------------------SPS-NQLRTVRIQLIRKKVCQRAYQG------RDTLTAST 189
                                     ||: ..||.:|::||.:..|...|..      .:......
Human   190 SAPNCPGFQSPLLPRSQTLAPAPSLSPAPGTLRNLRLRLISRPTCNCIYNQLHQRHLSNPARPGM 254

  Fly   190 FCA--RTGGKDSCSGDSGGGVIFKNQLC----------GIVSWGLGCANAQYPGVYTS 235
            .|.  :.|.:..|.|||||.|     ||          ||:|:...||....|.:.|:
Human   255 LCGGPQPGVQGPCQGDSGGPV-----LCLEPDGHWVQAGIISFASSCAQEDAPVLLTN 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	65/286 (23%)
PRSS53	XP_011544118.1	Tryp_SPc	42..316	CDD:238113	64/281 (23%)
		Tryp_SPc	359..>512	CDD:473915