Protein Alignment CG3650 and TMPRSS12

DIOPT Version :10

• Sequence 1: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_872365.2
• Gene: TMPRSS12 / 283471
• HGNCID: 28779
• Length: 348
• Species: Homo sapiens
• Alignment Length: 236
• Identity: 74/236 - (31%)
• Similarity: 113/236 - (47%)
• Gaps: 36/236 - (15%)

  Fly    25 RIVGGTTTTLSAVGGFVVNL--RYDGTF--YCGGSLVTSSHVVTAAHCLKGYQASRITVQGGV-- 83
            ||:|||.....| ..:||:|  :|....  .|||:||....|:|||||.|  .||...:...|
Human    77 RIIGGTEAQAGA-WPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTK--DASDPLMWTAVIG 138

  Fly    84 -----SKLSQSGVVRRVARYFIPNGFSSSSLNWDVGVIRLQSALTGSGITTIPLC----QVQWNP 139
                 .:...:..::..|....||....|.:| |:.:..|:.|:..:.... |:|    ..|...
Human   139 TNNIHGRYPHTKKIKIKAIIIHPNFILESYVN-DIALFHLKKAVRYNDYIQ-PICLPFDVFQILD 201

  Fly   140 GN-YMRVSGWGTTR-YGNSSPSNQLRTVRIQLIRKKVC--QRAYQGRDTLTASTFCA--RTGGKD 198
            || ...:||||.|: .||:  :|.|:...:..|.:::|  :|:|.|  .:..::|||  ..|..|
Human   202 GNTKCFISGWGRTKEEGNA--TNILQDAEVHYISREMCNSERSYGG--IIPNTSFCAGDEDGAFD 262

  Fly   199 SCSGDSGGGVI-----FKN-QLCGIVSWGLGCANAQYPGVY 233
            :|.|||||.::     :|. .:.||.|:|.||....:||||
Human   263 TCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVY 303

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	74/236 (31%)
TMPRSS12	NP_872365.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	24..46
		Tryp_SPc	78..316	CDD:238113	73/235 (31%)