Protein Alignment CG3650 and Cfd

DIOPT Version :10

• Sequence 1: NP_611971.1
• Gene: CG3650 / 37974
• FlyBaseID: FBgn0035070
• Length: 249
• Species: Drosophila melanogaster
• Sequence 2: NP_038487.1
• Gene: Cfd / 11537
• MGIID: 87931
• Length: 259
• Species: Mus musculus
• Alignment Length: 245
• Identity: 74/245 - (30%)
• Similarity: 121/245 - (49%)
• Gaps: 20/245 - (8%)

  Fly    13 LLLGLASGQIQP--RIVGGTTTTLSAVGGFVVNLRYDGTFYCGGSLVTSSHVVTAAHCLKGY-QA 74
            ::||.|....||  ||:||......| ..::.:::.:||..|||:|:....|::||||:.|. ..
Mouse    11 VILGAAVCAAQPRGRILGGQEAAAHA-RPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDD 74

  Fly    75 SRITVQGGVSKLSQSGVVRR--VARYFIPN-GFSSSSLNWDVGVIRL-QSALTGSGITTIPLCQV 135
            ..:.|..|...||.....:|  ..:..:|: |....||..|:.:.:| |:|..|..:..:||
Mouse    75 DSVQVLLGAHSLSAPEPYKRWYDVQSVVPHPGSRPDSLEDDLILFKLSQNASLGPHVRPLPL--- 136

  Fly   136 QW-----NPGNYMRVSGWGTTRYGNSSPSNQLRTVRIQLIRKKVCQ-RAYQGRDTLTASTFCART 194
            |:     .||....|:|||...:....| :.|..:|:.::.:..|. |.|.. ..:|.:..||.:
Mouse   137 QYEDKEVEPGTLCDVAGWGVVTHAGRRP-DVLHQLRVSIMNRTTCNLRTYHD-GVVTINMMCAES 199

  Fly   195 GGKDSCSGDSGGGVIFKNQLCGIVSWGLG-CANAQYPGVYTSVHRVRSFI 243
            ..:|:|.||||..::..:.:.|:|:||.. |.|.:.|||||.|...|.:|
Mouse   200 NRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWI 249

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3650	NP_611971.1	Tryp_SPc	25..243	CDD:214473	68/229 (30%)
Cfd	NP_038487.1	Tryp_SPc	26..252	CDD:238113	68/230 (30%)
		Self-inhibitor loop. /evidence=ECO:0000250|UniProtKB:P00746	224..228		2/3 (67%)