Protein Alignment Dll and pitx1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001035436.3
• Gene: pitx1 / 678598
• ZFINID: ZDB-GENE-060421-3623
• Length: 285
• Species: Danio rerio
• Alignment Length: 287
• Identity: 73/287 - (25%)
• Similarity: 107/287 - (37%)
• Gaps: 94/287 - (32%)

  Fly    79 MHQNSYSGYHLGSYAPPCASPPKD----------DFSISDK------CEDSGLRVNGKGKKMRKP 127
            |:.:..|.:||    |..||..::          |...::|      ..|.|...:.|.||.|:.
Zfish     1 MNVDMASSFHL----PRSASSTRETLENTSSESSDTEAAEKERSVEQRSDDGNADDPKKKKQRRQ 61

  Fly   128 RTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQ----- 187
            ||.::|.|||:|...|||.:|..:..|.|:|....||:.:|::||:|||:|::|..:..|
Zfish    62 RTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTEARVRVWFKNRRAKWRKRERNQQMDLCK 126

  Fly   188 -----------------------GPGTNSGM---PL--------GGGGPNPGQ---HSPNQMHSG 215
                                   ...||.|:   ||        ....|...|   .:|:.:.|.
Zfish   127 NSYLPQFSGLMQPYDDVYPTYTYNNWTNKGLTPAPLSTKNFTFFNSMSPLTSQSMFSAPSSISSM 191

  Fly   216 ELANGRFLWAALETNGTLAL--VHSTGGNNGGGSNSGSPSHYLPPGHSPT-PSSTPVSELS---- 273
            .:|:|.         |..|:  :.:||.||.|..|....|...|...|.| |...|||..|
Zfish   192 SMASGM---------GHSAVPGMPTTGLNNIGNLNGIGGSTINPAMSSSTCPYGPPVSPYSVYRD 247

  Fly   274 ----------------PEFPPTGLSPP 284
                            |.|..:||..|
Zfish   248 TCNSSLATLRLKSKQHPSFGYSGLQSP 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	24/55 (44%)
pitx1	NP_001035436.3	COG5576	8..>126	CDD:227863	38/121 (31%)
		Homeodomain	59..115	CDD:459649	24/55 (44%)
		OAR	247..263	CDD:461067	0/15 (0%)