DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dll and URAD

DIOPT Version :9

Sequence 1:NP_001137759.1 Gene:Dll / 37973 FlyBaseID:FBgn0000157 Length:347 Species:Drosophila melanogaster
Sequence 2:NP_001099047.1 Gene:URAD / 646625 HGNCID:17785 Length:173 Species:Homo sapiens


Alignment Length:72 Identity:16/72 - (22%)
Similarity:26/72 - (36%) Gaps:32/72 - (44%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 SGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQ---------------RT-------QYLALPERA 155
            :|||..|..:::|          |.:||.:::               ||       :.|..|...
Human    91 AGLRSLGADERLR----------LAELNAQYRARFGFPFVLAARFSDRTAVPRELARRLLCPSAQ 145

  Fly   156 ELAASLG 162
            ||..:||
Human   146 ELRTALG 152

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DllNP_001137759.1 Homeobox 127..180 CDD:278475 11/58 (19%)
URADNP_001099047.1 OHCU_decarbox 10..163 CDD:286439 16/72 (22%)
Substrate binding. /evidence=ECO:0000255 84..88
Substrate binding. /evidence=ECO:0000255 119..123 0/3 (0%)
Microbody targeting signal. /evidence=ECO:0000255 171..173
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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