DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dll and Vax2

DIOPT Version :9

Sequence 1:	NP_001137759.1	Gene:	Dll / 37973	FlyBaseID:	FBgn0000157	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_072159.1	Gene:	Vax2 / 64572	RGDID:	621133	Length:	292	Species:	Rattus norvegicus

Alignment Length:	262	Identity:	75/262 - (28%)
Similarity:	104/262 - (39%)	Gaps:	63/262 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 GYGGIRSTYQHFGPQG-GQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSIS 107
            |..|.|.  :|.|.:. ..|:|..|||...|         :.:....||......|..:.....:
  Rat    20 GRSGCRG--EHRGAEDLRADTGSTSPREIAG---------TSASSPAGSRESGGDSDGQQALGET 73

  Fly   108 DKCEDSGLR---------VNGKGKKMRKP---RTIYSSLQLQQLNRRFQRTQYLALPERAELAAS 160
            |.|....:|         |..||..:.:|   ||.:::.||.:|...|||.||:...||.|||..
  Rat    74 DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQ 138

  Fly   161 LGLTQTQVKIWFQNRRSKYKK----------MMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSG 215
            |.|::||||:||||||:|.||          ...|.:...|::.:.|
  Rat   139 LNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSAFEAFATSNVLRL------------------ 185

  Fly   216 ELANGRFLWAALETNGTLALVHSTGGNNGG--GSNSGSP---SHYLPPGHSPTPSSTPVSELSPE 275
             |..||.| :.......|||.....|...|  |::.|.|   |..|    :|.||::..|.|.|.
  Rat   186 -LEQGRLL-SVPRAPSLLALSPGLPGLTAGHRGTSLGDPRNSSQRL----NPMPSASASSPLPPP 244

  Fly   276 FP 277
            .|
  Rat   245 LP 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	29/55 (53%)
Vax2	NP_072159.1	vax upstream domain	74..101		6/26 (23%)
		homeobox	102..161		31/58 (53%)
		Homeobox	105..158	CDD:278475	28/52 (54%)
		vax downstream domain	182..193		5/30 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..241		10/32 (31%)
		vax terminal domain	266..274
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810