Protein Alignment Dll and Vax2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_072159.2
• Gene: Vax2 / 64572
• RGDID: 621133
• Length: 292
• Species: Rattus norvegicus
• Alignment Length: 262
• Identity: 75/262 - (28%)
• Similarity: 105/262 - (40%)
• Gaps: 63/262 - (24%)

  Fly    44 GYGGIRSTYQHFGPQG-GQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSIS 107
            |..|.|.  :|.|.:. ..|:|..|||...|         :.:....||......|..:.....:
  Rat    20 GRSGCRG--EHRGAEDLRADTGSTSPREIAG---------TSASSPAGSRESGGDSDGQQALGET 73

  Fly   108 DKCEDSGLR---------VNGKGKKMRKP---RTIYSSLQLQQLNRRFQRTQYLALPERAELAAS 160
            |.|....:|         |..||..:.:|   ||.:::.||.:|...|||.||:...||.|||..
  Rat    74 DHCRRILVRDAKGTIREIVLPKGLDLDRPKRTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQ 138

  Fly   161 LGLTQTQVKIWFQNRRSKYKK----------MMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSG 215
            |.|::||||:||||||:|.||          ...|::...|::.:.|
  Rat   139 LNLSETQVKVWFQNRRTKQKKDQSRDLEKRASSSASEAFATSNVLRL------------------ 185

  Fly   216 ELANGRFLWAALETNGTLALVHSTGGNNGG--GSNSGSP---SHYLPPGHSPTPSSTPVSELSPE 275
             |..||.| :.......|||.....|...|  |::.|.|   |..|    :|.||::..|.|.|.
  Rat   186 -LEQGRLL-SVPRAPSLLALSPGLPGLTAGHRGTSLGDPRNSSQRL----NPMPSASASSPLPPP 244

  Fly   276 FP 277
            .|
  Rat   245 LP 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/58 (50%)
Vax2	NP_072159.2	vax upstream domain	74..101		6/26 (23%)
		homeobox	102..161		31/58 (53%)
		Homeodomain	103..159	CDD:459649	28/55 (51%)
		vax downstream domain	182..193		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	212..241		10/32 (31%)
		vax terminal domain	266..274