Protein Alignment Dll and Vax1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_072158.1
• Gene: Vax1 / 64571
• RGDID: 621132
• Length: 336
• Species: Rattus norvegicus
• Alignment Length: 268
• Identity: 64/268 - (23%)
• Similarity: 90/268 - (33%)
• Gaps: 106/268 - (39%)

  Fly    90 GSYAPPCASPPKDDFSISDKCED------------------------SGLR--VNGKGKKMRKP- 127
            ||........|:..||.|...||                        ..:|  :..||..:.:|
  Rat    37 GSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPK 101

  Fly   128 --RTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKK--------- 181
              ||.:::.||.:|...|||.||:...||.|||..|.|::||||:||||||:|.||
  Rat   102 RTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELR 166

  Fly   182 --------------------------------------MMKAAQGP-------GTNSGM------ 195
                                                  :..|.:||       |..:|.
  Rat   167 SVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAA 231

  Fly   196 ---------------PLGGGGPNPGQHSPNQMHSG--ELANGRFLWAALETNGTLALVHSTGGNN 243
                           |..||.|.||...|..:|:|  ..::|.|........|::|...|:....
  Rat   232 AATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLT 296

  Fly   244 GGGSNSGS 251
            ..||.:|:
  Rat   297 MAGSLAGN 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/58 (50%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..39		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	50..69		5/18 (28%)
		vax upstream domain	72..99		3/26 (12%)
		homeobox	100..159		31/58 (53%)
		Homeodomain	101..157	CDD:459649	28/55 (51%)
		vax downstream domain	178..189		0/10 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	236..267		8/30 (27%)
		vax terminal domain	315..323