DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Dll and Vax1

DIOPT Version :9

Sequence 1:	NP_001137759.1	Gene:	Dll / 37973	FlyBaseID:	FBgn0000157	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_072158.1	Gene:	Vax1 / 64571	RGDID:	621132	Length:	336	Species:	Rattus norvegicus

Alignment Length:	268	Identity:	64/268 - (23%)
Similarity:	90/268 - (33%)	Gaps:	106/268 - (39%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 GSYAPPCASPPKDDFSISDKCED------------------------SGLR--VNGKGKKMRKP- 127
            ||........|:..||.|...||                        ..:|  :..||..:.:|
  Rat    37 GSLPAAFLKEPQGAFSASGASEDCNKSKSNSSADPDYCRRILVRDAKGSIREIILPKGLDLDRPK 101

  Fly   128 --RTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKK--------- 181
              ||.:::.||.:|...|||.||:...||.|||..|.|::||||:||||||:|.||
  Rat   102 RTRTSFTAEQLYRLEMEFQRCQYVVGRERTELARQLNLSETQVKVWFQNRRTKQKKDQGKDSELR 166

  Fly   182 --------------------------------------MMKAAQGP-------GTNSGM------ 195
                                                  :..|.:||       |..:|.
  Rat   167 SVVSETAATCSVLRLLEQGRLLSPPGLPALLPPCATGALGSALRGPSLPALGAGAAAGSAAAAAA 231

  Fly   196 ---------------PLGGGGPNPGQHSPNQMHSG--ELANGRFLWAALETNGTLALVHSTGGNN 243
                           |..||.|.||...|..:|:|  ..::|.|........|::|...|:....
  Rat   232 AATAPGPAGAASQHPPAVGGAPGPGPAGPGGLHAGAPTASHGLFSLPVPSLLGSVASRLSSAPLT 296

  Fly   244 GGGSNSGS 251
            ..||.:|:
  Rat   297 MAGSLAGN 304

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeobox	127..180	CDD:278475	29/55 (53%)
Vax1	NP_072158.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..39		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	50..69		5/18 (28%)
		vax upstream domain	72..99		3/26 (12%)
		homeobox	100..159		31/58 (53%)
		Homeobox	103..156	CDD:278475	28/52 (54%)
		vax downstream domain	178..189		0/10 (0%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..267		8/30 (27%)
		vax terminal domain	315..323
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0850
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810