Protein Alignment Dll and dlx3

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001025566.1
• Gene: dlx3 / 594954
• XenbaseID: XB-GENE-5879293
• Length: 276
• Species: Xenopus tropicalis
• Alignment Length: 280
• Identity: 104/280 - (37%)
• Similarity: 124/280 - (44%)
• Gaps: 83/280 - (29%)

  Fly    59 GGQDSGFP----SPR-SALGYPFPPMHQNSYS------------------GYH-LGSYAPPCASP 99
            |||...|.    ||. |:.|| ..|.||.:::                  ||. .|.|..|   |
 Frog    46 GGQHDFFQTQAYSPSISSYGY-HHPHHQYNFNGLVGNESFLPKDDYQYGGGYRAFGHYREP---P 106

  Fly   100 PKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLT 164
            ..:..|:.::.|.....||||.||:|||||||||.||..|.||||:.|||||||||||||.||||
 Frog   107 VPETVSVKEEPETEVRMVNGKPKKIRKPRTIYSSYQLAALQRRFQKAQYLALPERAELAAQLGLT 171

  Fly   165 QTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALET 229
            ||||||||||||||:||:.|..:|||.              :|||
 Frog   172 QTQVKIWFQNRRSKFKKLYKTGEGPGL--------------EHSP-------------------- 202

  Fly   230 NGTLALVHSTGGNNGGGSNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPTQA----PW- 289
                        ||.......|||.  ||....:.|.||..:.....||  .|.|:..    ||
 Frog   203 ------------NNSDSMACNSPSS--PPVWDNSRSRTPQQQQQQSLPP--CSSPSYMENYHPWY 251

  Fly   290 DQKPHWIDHKPPPQMTPQPP 309
            .|:.....|..|.::..|||
 Frog   252 TQQTQPGQHLQPSEVMHQPP 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	47/55 (85%)
dlx3	NP_001025566.1	DLL_N	24..110	CDD:463567	18/67 (27%)
		COG5576	109..227	CDD:227863	72/165 (44%)
		Homeodomain	132..188	CDD:459649	47/55 (85%)