Protein Alignment Dll and nkx2.4b

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_571664.1
• Gene: nkx2.4b / 58112
• ZFINID: ZDB-GENE-000830-1
• Length: 307
• Species: Danio rerio
• Alignment Length: 299
• Identity: 76/299 - (25%)
• Similarity: 111/299 - (37%)
• Gaps: 81/299 - (27%)

  Fly    18 TAASVTPGINIPGKSAFVELQQHAAA--GYGGIRSTYQHFGPQGGQDSGF--------------- 65
            ::||:...:....:.:...||||:.:  .|....|.:.| ...||..:|.
Zfish    32 SSASLASPLYRQSQVSQANLQQHSMSHNAYHMPHSQFSH-STMGGYCNGTIGAMGDLPSYQESMR 95

  Fly    66 ------------PSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVN 118
                        |.||    ||.........:|.::|:.       |..|.|.|        .|.
Zfish    96 NGATATAWYGSNPEPR----YPTISRFMGPSAGMNMGTL-------PGMDASKS--------MVT 141

  Fly   119 GKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMM 183
            ......||.|.::|..|:.:|.|||::.:||:.|||..||:.:.||.|||||||||.|.|.|:..
Zfish   142 LHAAPRRKRRVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQA 206

  Fly   184 KAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSN 248
            |.......:||...       .|.||.::                   .|.::...|.....||.
Zfish   207 KDKASQQQDSGNMC-------AQQSPRRV-------------------ALPVLVKDGKPCQNGSG 245

  Fly   249 SGSPSHYLPP---GHSPTPSSTPVSELSPEFPPT--GLS 282
            :.:|.|....   |.....|:..:.|:||. ||.  |||
Zfish   246 TPTPIHQQVQSVLGSETLASAEDLEEMSPS-PPLMGGLS 283

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)
nkx2.4b	NP_571664.1	Homeodomain	148..204	CDD:459649	29/55 (53%)