Protein Alignment Dll and nkx2.4a

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001104636.1
• Gene: nkx2.4a / 562300
• ZFINID: ZDB-GENE-030131-6336
• Length: 345
• Species: Danio rerio
• Alignment Length: 324
• Identity: 77/324 - (23%)
• Similarity: 114/324 - (35%)
• Gaps: 126/324 - (38%)

  Fly     7 PHTPKYMD----GGNTAASVTPGINIPGKSAFVELQQHAAA--GYGGIR-----STYQHF-GPQG 59
            ||:.....    ||....|:.   |:....::.|..:::||  |:.|..     ||...| ||..
Zfish    71 PHSVSQFSHSAMGGYCNGSIA---NMGDLPSYQETMRNSAAATGWYGANPDPRYSTISRFMGPST 132

  Fly    60 GQD-------SGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRV 117
            |.:       :|......::    ||:|                |:|
Zfish   133 GMNMTGMGTLTGMADTTKSI----PPLH----------------AAP------------------ 159

  Fly   118 NGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKM 182
                  .||.|.::|..|:.:|.|||::.:||:.|||..||:.:.||.|||||||||.|.|.|:.
Zfish   160 ------RRKRRVLFSQAQVCELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQ 218

  Fly   183 M--KAA-------------QGPG-------TNSGMPLGGGGPNPGQHSPNQMHSGELANGRFLWA 225
            .  |||             |.|.       ...|.|...|...|   :|||....:
Zfish   219 AKDKAAQQLQQEGNLCQQQQSPRRVAVPVLVKDGKPCQNGSNTP---TPNQQQMQQ--------- 271

  Fly   226 ALETNGTLALVHSTGGNNGGG----SNSGSPSHYLPPGHSPTPSSTPVSELSPEFPPTGLSPPT 285
                           ..||||    ::|.|.:.:.....:....:..:.|:||       |||:
Zfish   272 ---------------QQNGGGVVLPTSSNSMNQHQSQQVNALVQAQDLEEMSP-------SPPS 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)
nkx2.4a	NP_001104636.1	Homeodomain	161..217	CDD:459649	29/55 (53%)