Protein Alignment Dll and PRRX1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_073207.1
• Gene: PRRX1 / 5396
• HGNCID: 9142
• Length: 245
• Species: Homo sapiens
• Alignment Length: 152
• Identity: 43/152 - (28%)
• Similarity: 68/152 - (44%)
• Gaps: 28/152 - (18%)

  Fly   107 SDKCEDSGLRVNGKGKKMRKP---RTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQV 168
            ||..:....::|.:.||.||.   ||.::|.|||.|.|.|:||.|.....|.:||..:.||:.:|
Human    74 SDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDLARRVNLTEARV 138

  Fly   169 KIWFQNRRSKYKK------------MMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGR 221
            ::||||||:|:::            ::|:..|..|....|:   .|.|.....:.:.
Human   139 QVWFQNRRAKFRRNERAMLANKNASLLKSYSGDVTAVEQPI---VPRPAPRPTDYLS-------- 192

  Fly   222 FLWAALETNGTLALVHSTGGNN 243
              |........:|...:|..||
Human   193 --WGTASPYSAMATYSATCANN 212

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	27/58 (47%)
PRRX1	NP_073207.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..22
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	63..103		9/28 (32%)
		Homeodomain	99..151	CDD:459649	24/51 (47%)
		OAR	219..235	CDD:461067
		OAR. /evidence=ECO:0000255|PROSITE-ProRule:PRU00138	222..235