Protein Alignment Dll and En2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001102684.1
• Gene: En2 / 499964
• RGDID: 1561842
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 193
• Identity: 54/193 - (27%)
• Similarity: 77/193 - (39%)
• Gaps: 51/193 - (26%)

  Fly    17 NTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQ------------------GGQD- 62
            |.|.:.:.|..:.|.|.     ..||.|.||.::...|.|.:                  ||.|
  Rat   122 NPACAPSAGGPLSGASG-----DPAADGEGGSKTLSLHGGAKKPGDPGGSLDGALKARGLGGGDL 181

  Fly    63 ---SGFPSPRSALGYPFPPM------HQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVN 118
               |...|.:::......||      :...||  ...|..|....|.|.:.:..||
  Rat   182 SVSSDSDSSQASATLGAQPMLWPAWVYCTRYS--DRPSSGPRSRKPKKKNPNKEDK--------- 235

  Fly   119 GKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKK 181
                   :|||.:::.|||:|...||..:||....|..||..|.|.::|:||||||:|:|.||
  Rat   236 -------RPRTAFTAEQLQRLKAEFQTNRYLTEQRRQSLAQELSLNESQIKIWFQNKRAKIKK 291

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	25/55 (45%)
En2	NP_001102684.1	Homeodomain	235..291	CDD:459649	26/71 (37%)
		Engrail_1_C_sig	292..322	CDD:431338	54/193 (28%)