DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Dll and Emx2

DIOPT Version :9

Sequence 1:NP_001137759.1 Gene:Dll / 37973 FlyBaseID:FBgn0000157 Length:347 Species:Drosophila melanogaster
Sequence 2:NP_001102639.1 Gene:Emx2 / 499380 RGDID:1564797 Length:253 Species:Rattus norvegicus


Alignment Length:224 Identity:63/224 - (28%)
Similarity:95/224 - (42%) Gaps:60/224 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 DAP------DAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGG 60
            |:|      :.|..|..:...| ::.:.|.:|     .|......||||    |..|.:      
  Rat    19 DSPLPASRSEDPIRPAALSYAN-SSPINPFLN-----GFHSAAAAAAAG----RGVYSN------ 67

  Fly    61 QDSGF-------PSPRSALGYPFPPMH-------QNSYSGYHLGSYAPPCASPPKDD-------- 103
            .|..|       |:|...: :|.||.|       .:|:|.:      |..||..:|.        
  Rat    68 PDLVFAEAVSHPPNPAVPV-HPVPPPHALAAHPLPSSHSPH------PLFASQQRDPSTFYPWLI 125

  Fly   104 ---------FSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAA 159
                     |..:|...:|.|..|...:|.::.||.:|..||.:|...|::..|:...||.:||.
  Rat   126 HRYRYLGHRFQGNDTSPESFLLHNALARKPKRIRTAFSPSQLLRLEHAFEKNHYVVGAERKQLAH 190

  Fly   160 SLGLTQTQVKIWFQNRRSKYKKMMKAAQG 188
            ||.||:||||:||||||:|:|:.....:|
  Rat   191 SLSLTETQVKVWFQNRRTKFKRQKLEEEG 219

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
DllNP_001137759.1 Homeobox 127..180 CDD:278475 27/52 (52%)
Emx2NP_001102639.1 Homeobox 159..212 CDD:395001 27/52 (52%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0850
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
32.810

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