Protein Alignment Dll and dlx2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001008061.1
• Gene: dlx2 / 493423
• XenbaseID: XB-GENE-852891
• Length: 285
• Species: Xenopus tropicalis
• Alignment Length: 317
• Identity: 114/317 - (35%)
• Similarity: 132/317 - (41%)
• Gaps: 120/317 - (37%)

  Fly    38 QQHAAAG--YGGIRSTYQHFGPQGGQDSGFPSPRSALGY---PFPPMHQNSYSGYHLGSY----A 93
            |||..||  ||.:.| ||..|          :..:.:.|   .:...:..|||.|  |.|    :
 Frog    51 QQHCGAGSPYGQLGS-YQFHG----------AALNGISYSTKSYDLTYSGSYSSY--GPYGTSPS 102

  Fly    94 PPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELA 158
            ||...|.|:|      ||.....||||.||:|||||||||.||..|.||||:|||||||||||||
 Frog   103 PPHNDPEKED------CEPEVRMVNGKPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELA 161

  Fly   159 ASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNPGQHSPNQMHSGELANGRFL 223
            ||||||||||||||||||||:|||.|                             |||:
 Frog   162 ASLGLTQTQVKIWFQNRRSKFKKMWK-----------------------------SGEI------ 191

  Fly   224 WAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPG-HSPTPSSTPVSELSPEFPPTGLSPPTQA 287
                                        ||..||.| .|||.:|.|.|               .|
 Frog   192 ----------------------------PSDQLPVGSESPTCNSPPAS---------------TA 213

  Fly   288 PWDQKPHWIDHKPPPQMTPQPPHPAATLHPQTHHHNPPPQMGGYVPQYWYQPETNPS 344
            .||..||         ...|.....:.|.......:|.|.:|.|   .||| .:||:
 Frog   214 TWDFGPH---------QRLQGAASGSALQSSNSASSPSPFLGNY---SWYQ-TSNPA 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	49/55 (89%)
dlx2	NP_001008061.1	DLL_N	29..107	CDD:463567	20/68 (29%)
		Homeodomain	128..184	CDD:459649	49/55 (89%)