Protein Alignment Dll and MSX2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 136
• Identity: 55/136 - (40%)
• Similarity: 75/136 - (55%)
• Gaps: 26/136 - (19%)

  Fly    59 GGQDSGFPSPRSALGYPFPP---MHQNSYSG----YHLGSYAPP--CASPPKDDFSISDKCEDSG 114
            |.:::..|.|   |..||..   ..:||..|    ...|.|:||  ..||        ..|.
Human    85 GAREAHSPGP---LVKPFETASVKSENSEDGAAWMQEPGRYSPPPRHMSP--------TTCT--- 135

  Fly   115 LRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKY 179
            ||   |.|..|||||.:::.||..|.|:|::.|||::.||||.::||.||:|||||||||||:|.
Human   136 LR---KHKTNRKPRTPFTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKA 197

  Fly   180 KKMMKA 185
            |::.:|
Human   198 KRLQEA 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	33/55 (60%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		14/44 (32%)
		Homeodomain	143..199	CDD:459649	33/55 (60%)