Protein Alignment Dll and nkx6.1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001002475.1
• Gene: nkx6.1 / 436748
• ZFINID: ZDB-GENE-040718-178
• Length: 312
• Species: Danio rerio
• Alignment Length: 283
• Identity: 79/283 - (27%)
• Similarity: 108/283 - (38%)
• Gaps: 72/283 - (25%)

  Fly     1 MDAPDAPHTPKYMDG-----GNTAASVTPGINIP----------GKSAFVELQQHAAAGYGGIRS 50
            |..|..|..|....|     ..||.|..|| .||          |.||....||.|.|...||..
Zfish    31 MKTPLYPAYPLSSTGPASSTSPTATSPNPG-GIPVSSPGIKTSSGLSALASAQQCAIATPHGIND 94

  Fly    51 TYQHFGPQ-----GGQDSGFPSPRSALGYPFPP--MHQNSYSGYHLGSYAPPCA----------- 97
            ....  |.     .|..||.|. .|:|..|.||  ....|.:...:..|..|..
Zfish    95 ILSR--PSVACSPAGILSGLPR-FSSLSPPPPPGLYFSPSAAAVAVARYPKPLTELPGRTPIFWP 156

  Fly    98 ----SPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELA 158
                ||...|...:.....:.:.::..||: :..|..:|..|:..|.:.|::|:|||.||||.||
Zfish   157 GVMQSPHWRDARFACSPHQNSVLLDKDGKR-KHTRPTFSGQQIFALEKTFEQTKYLAGPERARLA 220

  Fly   159 ASLGLTQTQVKIWFQNRRSKYKKM----MKAAQGPGTNSGMPLGGGGPNPG-------------- 205
            .|||:|::|||:||||||:|::|.    |.:|:....:....|.|...|..
Zfish   221 YSLGMTESQVKVWFQNRRTKWRKRHAAEMASAKKKQDSETERLKGASENEDDDDDYNKPLDPNSD 285

  Fly   206 ---------QHSPNQ---MHSGE 216
                     :|.||.   :|:.|
Zfish   286 DEKITQLLKKHKPNSALIIHTSE 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	29/55 (53%)
nkx6.1	NP_001002475.1	Homeodomain	185..243	CDD:459649	30/58 (52%)