Protein Alignment Dll and MEOX1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_004518.1
• Gene: MEOX1 / 4222
• HGNCID: 7013
• Length: 254
• Species: Homo sapiens
• Alignment Length: 232
• Identity: 62/232 - (26%)
• Similarity: 95/232 - (40%)
• Gaps: 69/232 - (29%)

  Fly     4 PD--APHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHF----------- 55
            ||  |..|..|.|...:..:.||. ::| :...:..:||.|..    :|...||
Human    49 PDFLATATAAYPDFSASCLAATPH-SLP-QEEHIFTEQHPAFP----QSPNWHFPVSDARRRPNS 107

  Fly    56 GPQGG-QDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSI------------S 107
            ||.|| ::.|    .|:||.      .::..|             |.||:.:            |
Human   108 GPAGGSKEMG----TSSLGL------VDTTGG-------------PGDDYGVLGSTANETEKKSS 149

  Fly   108 DKCEDSGLRVNGKGK-----KMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQ 167
            .:.::|......:||     |.||.||.::..||::|...|....||....|.|:|.:|.|::.|
Human   150 RRRKESSDNQENRGKPEGSSKARKERTAFTKEQLRELEAEFAHHNYLTRLRRYEIAVNLDLSERQ 214

  Fly   168 VKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGPNP 204
            ||:||||||.|:|::         ..|.|:...|.:|
Human   215 VKVWFQNRRMKWKRV---------KGGQPISPNGQDP 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	25/55 (45%)
MEOX1	NP_004518.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	86..178		25/118 (21%)
		Homeodomain	172..228	CDD:459649	25/55 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	227..254		5/25 (20%)