Protein Alignment Dll and Nanog

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_001094251.1
• Gene: Nanog / 414065
• RGDID: 1303178
• Length: 312
• Species: Rattus norvegicus
• Alignment Length: 308
• Identity: 82/308 - (26%)
• Similarity: 123/308 - (39%)
• Gaps: 74/308 - (24%)

  Fly    56 GP------QGGQDSGFPSPRSALGYPFPPMHQNSYSGYHLGSYAPPC---ASPP--KDDFSISDK 109
            ||      :...:||..||..|:..|     :.:||...:.:....|   ||||  ..|..:.|.
  Rat     7 GPHSLPSCEEASNSGDSSPMPAVHLP-----EENYSCLQVSATEMLCTETASPPPSSGDLPLQDS 66

  Fly   110 CEDSG---LRVNG----KG----------KKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAEL 157
            .:.|.   |:::|    :|          .|.:|.||::|..||..|..||||.:||:|.:..:|
  Rat    67 PDSSSNPKLKLSGPEADEGPEKKEENKVLTKKQKMRTVFSQAQLCALKDRFQRQRYLSLQQMQDL 131

  Fly   158 AASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGMPLGGGGP--NPGQH-SPNQMH----SG 215
            :..|.|:..|||.||||:|.|.|:..| .|...|::|:...|..|  .|..| |.:|.:    ||
  Rat   132 STILNLSYKQVKTWFQNQRMKCKRWQK-NQWLKTSNGLTQKGSAPVEYPSIHCSYSQGYLMNASG 195

  Fly   216 ELANGRFLWAALE-----------TNGTLA---LVHSTGGNNGGGSNS------GSPSHYLPPGH 260
            .|.    :|.:..           ||.|.:   ..:.|..|....:.|      .|.:....|.|
  Rat   196 NLP----VWGSQTWTNPTWNNQTWTNPTWSNQTWTNPTWSNQAWSTQSWCTQAWNSQTWNAAPLH 256

  Fly   261 S-PTPSSTPVSELSPEFPPTGLSPPTQAPWDQKPHWIDHKPPPQMTPQ 307
            : ...|..|...|...|..:.|....:|..:.:.|:        .|||
  Rat   257 NFGEDSLQPYVPLQQNFSASDLEANLEATRESQAHF--------STPQ 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	26/55 (47%)
Nanog	NP_001094251.1	Homeodomain	100..155	CDD:459649	26/54 (48%)
		PTZ00395	<184..>291	CDD:185594	21/110 (19%)