Protein Alignment Dll and msx2

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: XP_002936749.1
• Gene: msx2 / 394987
• XenbaseID: XB-GENE-852974
• Length: 256
• Species: Xenopus tropicalis
• Alignment Length: 294
• Identity: 74/294 - (25%)
• Similarity: 106/294 - (36%)
• Gaps: 122/294 - (41%)

  Fly     1 MDAPDAPHTPKYMDGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGF 65
            :||..|..||:::..|...:...||:....:::             .::|.....|....:|.|.
 Frog    59 VDASAAGSTPRHLHMGIRDSPSPPGLTKTFETS-------------SVKSENSEDGTTWSKDGGS 110

  Fly    66 PSPRSALGYPFPPMHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGLRVNGKGKKMRKPRTI 130
            .||        ||.|                .||        ..|.   ||   |.|..|||||.
 Frog   111 YSP--------PPRH----------------LSP--------STCT---LR---KHKTNRKPRTP 137

  Fly   131 YSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKMMKAAQGPGTNSGM 195
            :::.||..|.|:|::.|||::.||||.::||.||:|||||||||||:|.|::.:|.......:..
 Frog   138 FTTSQLLALERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAEIEKLKMAAK 202

  Fly   196 PLGGGGPNPGQHSPNQMHSGELANGRFLWAALETNGTLALVHSTGGNNGGGSNSGSPSHYLPPGH 260
            |:                                                          ||||.
 Frog   203 PI----------------------------------------------------------LPPGF 209

  Fly   261 S-PTPSSTPVSELS----------P--EFPPTGL 281
            | |.|.::|:...|          |  ..||.||
 Frog   210 SIPFPINSPIQAASLYGSSYQFHRPVLPIPPVGL 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	33/55 (60%)
msx2	XP_002936749.1	Homeodomain	132..188	CDD:459649	33/55 (60%)