Protein Alignment Dll and en

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_523700.2
• Gene: en / 36240
• FlyBaseID: FBgn0000577
• Length: 552
• Species: Drosophila melanogaster
• Alignment Length: 247
• Identity: 64/247 - (25%)
• Similarity: 94/247 - (38%)
• Gaps: 72/247 - (29%)

  Fly     4 PDAP--HTPKYMDGGNTAASVTPGIN---IPGKSAFVELQQHAAAGYGGIRSTY-----QHFGPQ 58
            |.||  ..|......::.||..|..|   |...|:.......:::|.....|:.     ...|..
  Fly   309 PAAPTMTQPPLSSSASSLASPPPASNASTISSTSSVATSSSSSSSGCSSAASSLNSSPSSRLGAS 373

  Fly    59 G-GQDSGFPSPRSALGYPFPP---------MHQNSYSGYHLGS-------------------YAP 94
            | |.::..|.|:     |.||         |..:..:....||                   |:.
  Fly   374 GSGVNASSPQPQ-----PIPPPSAVSRDSGMESSDDTRSETGSTTTEGGKNEMWPAWVYCTRYSD 433

  Fly    95 -PCASP----PKDDFSISDKCEDSGLRVNGKGKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPER 154
             |.:.|    ||..   .||..|.           ::|||.:||.||.:|.|.|...:||....|
  Fly   434 RPSSGPRYRRPKQP---KDKTNDE-----------KRPRTAFSSEQLARLKREFNENRYLTERRR 484

  Fly   155 AELAASLGLTQTQVKIWFQNRRSKYKK---------MMKAAQGPGTNSGMPL 197
            .:|::.|||.:.|:||||||:|:|.||         :...|||...::.:||
  Fly   485 QQLSSELGLNEAQIKIWFQNKRAKIKKSTGSKNPLALQLMAQGLYNHTTVPL 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	26/55 (47%)
en	NP_523700.2	Homeodomain	455..511	CDD:459649	26/55 (47%)
		Engrail_1_C_sig	512..542	CDD:431338	5/25 (20%)