Protein Alignment Dll and HOXD12

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_067016.3
• Gene: HOXD12 / 3238
• HGNCID: 5135
• Length: 270
• Species: Homo sapiens
• Alignment Length: 212
• Identity: 48/212 - (22%)
• Similarity: 82/212 - (38%)
• Gaps: 49/212 - (23%)

  Fly    26 IISLGNPSLDH---VFGGGFPI-GSIIGIEDKHGNYARVLSKYFLAEGIVNKHPLVVAIMDEDAT 86
            ::..|.|:..|   :|.|...| ..|:..|.:..|...:||.:  ....|:|:|  ..|..||..
Human    51 LVWTGEPTTKHFSDIFLGRCLIYTQILRPEMRDQNCQEILSTF--KGAFVSKNP--CNITREDYA 111

  Fly    87 QLINKLPTPLEESKTADNNSTMPEPETMRIAFRYNQLTPVDSEQKPATSLGHYFDLTKTMSPDML 151
            .|: ||.|     :|...|.|:...::..:|.:|..:.            |..|.|     .|.|
Human   112 PLV-KLVT-----QTIPCNKTLFWSKSKHLAHQYTWIQ------------GKMFTL-----EDTL 153

  Fly   152 LAH--DVTCWNGGELETNAPEFGSFNNPHYASLLSCIRS------KAGEQQFNAASDESSKNVLR 208
            |.:  |...|.|   :.:..:....:.||::.  :|..:      |...|:|    .|.:..|::
Human   154 LGYIADDLRWCG---DPSTSDMNYVSCPHWSE--NCPNNPITVFWKVISQKF----AEDACGVVQ 209

  Fly   209 ICLN-SMGSPLWYGKQF 224
            :.|| |:..|.:....|
Human   210 VMLNGSLREPFYKNSTF 226

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	11/57 (19%)
HOXD12	NP_067016.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	102..122		9/27 (33%)
		Homeodomain	203..259	CDD:459649	6/24 (25%)