Protein Alignment Dll and HOXD1

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_078777.1
• Gene: HOXD1 / 3231
• HGNCID: 5132
• Length: 328
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 68/229 - (29%)
• Similarity: 86/229 - (37%)
• Gaps: 61/229 - (26%)

  Fly    14 DGGNTAASVTPGINIPGKSAFVELQQHAAAGYGGIRSTYQHFGPQGGQDSGFPSPRSALGYPFPP 78
            |||:.....|..:...|.|..:..|...||           ||..|               |||.
Human   127 DGGSHVHYATSAVFSGGGSFLLSGQVDYAA-----------FGEPG---------------PFPA 165

  Fly    79 MHQNSYSGYHLGSYAPPCASPPKDDFSISDKCEDSGL--------------RVNGKGKKMR---- 125
            ..:.|..| |.|::.....:|.....|:|..   |||              ..:.|||...
Human   166 CLKASADG-HPGAFQTASPAPGTYPKSVSPA---SGLPAAFSTFEWMKVKRNASKKGKLAEYGAA 226

  Fly   126 KP----RTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKKM---- 182
            .|    ||.:|:.||.:|.:.|...:||....|.|:|..|.|..|||||||||||.|.||.
Human   227 SPSSAIRTNFSTKQLTELEKEFHFNKYLTRARRIEIANCLHLNDTQVKIWFQNRRMKQKKREREG 291

  Fly   183 MKAAQGPGTNSGMPLGGGGP-----NPGQHSPNQ 211
            :.|...|.....:||.|..|     |||..|.:|
Human   292 LLATAIPVAPLQLPLSGTTPTKFIKNPGSPSQSQ 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	27/63 (43%)
HOXD1	NP_078777.1	Antp-type hexapeptide	204..209		0/4 (0%)
		Homeodomain	233..286	CDD:459649	26/52 (50%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	305..328		9/21 (43%)