Protein Alignment Dll and HOXC10

DIOPT Version :10

• Sequence 1: NP_001137759.1
• Gene: Dll / 37973
• FlyBaseID: FBgn0000157
• Length: 347
• Species: Drosophila melanogaster
• Sequence 2: NP_059105.2
• Gene: HOXC10 / 3226
• HGNCID: 5122
• Length: 342
• Species: Homo sapiens
• Alignment Length: 196
• Identity: 57/196 - (29%)
• Similarity: 82/196 - (41%)
• Gaps: 43/196 - (21%)

  Fly     9 TPKYMDGGNTAASVTPGINIPGKSAF-VELQQHAAAGYGGIRSTYQHF-GPQGGQDSGFP-SPRS 70
            :|.|     :|...||  :..|.:.| ...:|.|:     :....:|. .||.|....|| :|:|
Human   152 SPSY-----SALDKTP--HCSGANDFEAPFEQRAS-----LNPRAEHLESPQLGGKVSFPETPKS 204

  Fly    71 ALGYPFPPMHQNSYSGYHLGSYAPPCASP---PKDDFSISDKCED---------------SGLRV 117
            ....|.|...:...      |.|.|..||   .|:....:|...|               :|..:
Human   205 DSQTPSPNEIKTEQ------SLAGPKGSPSESEKERAKAADSSPDTSDNEAKEEIKAENTTGNWL 263

  Fly   118 NGK-GKKMRKPRTIYSSLQLQQLNRRFQRTQYLALPERAELAASLGLTQTQVKIWFQNRRSKYKK 181
            ..| |:|.|.|.|.:.:|:|:   :.|....||....|.|::.::.||..||||||||||.|.||
Human   264 TAKSGRKKRCPYTKHQTLELE---KEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKK 325

  Fly   182 M 182
            |
Human   326 M 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Dll	NP_001137759.1	Homeodomain	125..181	CDD:459649	23/55 (42%)
HOXC10	NP_059105.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	187..271		20/89 (22%)
		Homeodomain	269..325	CDD:459649	24/58 (41%)